Hypocholesterolemic and Growth Promoting Effects of &amp;lt;i&amp;gt;Lactobacillus plantarum&amp;lt;/i&amp;gt; AK Isolated from a Nigerian Fermented Cereal Product on Rats Fed High Fat Diet

Akanbi, B. O.; Agarry, O. O.

doi:10.4236/aim.2014.43021

Cited by 4 publications

(3 citation statements)

References 21 publications

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“…The microbial population in the cecum provides evidence for cecal fermentation (Liyanage et al, ). Although there was no difference in Bifidobacteria and Lactobacilli populations among experimental groups, lower cecal coliform population in mung bean diet‐fed rats compared to the control group indicated that mung bean diets may have improved the cecal microbial balance in rats as suggested previously (Akanbi & Agarry, ).…”

Section: Resultssupporting

confidence: 65%

Hypolipidemic and hypoglycemic potential of raw, boiled, and sprouted mung beans (Vigna radiataL. Wilczek) in rats

et al. 2017

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This study was carried out to investigate the hypolipidemic and hypoglycemic potential of raw, boiled, and sprouted mung beans in rats. Oven dried mung bean powders; raw, sprouted, and boiled were included at 30% level in the diet of seven weeks old male Wistar rats maintained for 5 weeks on high (0.5%) cholesterol diet in comparison with control diet. Low serum glucose and triglyceride concentrations (p < .05) in raw and processed mung bean diets fed rats were supported by low serum insulin level in both raw mung bean diet and boiled mung bean diet fed rats. Hypoglycemic effect in sprouted mung bean fed rats was supported by higher α‐amylase inhibitory activity and α‐glucosidase inhibitory activity of sprouted mung beans. Increase in serum non‐HDL cholesterol concentration and decrease in HDL cholesterol concentration caused by high cholesterol diet were modulated (p < .05) by both boiled and sprouted mung bean diets. Practical applications Mung bean is a green legume rich in protein, fiber, antioxidants, and phytonutrients. Hypocholesterolemic and hypoglycemic potential of raw mung beans have been shown previously. It is well known that cooking and processing modulate nutritional and biochemical parameters of foods. However, very limited information is available on the effect of processing on functional properties of legumes. Results of this study showed that boiling and sprouting improved the soluble fiber content and hypocholesterolemic potential of mung beans. Thus, the processed mung beans may be more suitable for developing food supplements for patients with hypercholesterolemia.

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Section: Resultssupporting

confidence: 65%

Hypolipidemic and hypoglycemic potential of raw, boiled, and sprouted mung beans (Vigna radiataL. Wilczek) in rats

et al. 2017

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“…The main function of serum LDL is to transport the cholesterol synthesized by the liver to the tissue, and the main function of serum HDL is to transport the excess cholesterol from the tissue back to the liver for degradation [ 33 ]. In this study, compared with that of the control, the serum LDL content of weaned piglets treated with FBSPW did not change significantly, and the serum HDL content increased, especially in the piglets treated with 8% FBSPW, corroborating the results of Akanbi and Agarry [ 34 ]. These results indicate that the addition of FBSPW to the feed of weaned piglets improved the protein and lipid metabolisms of piglets, and this may be related to the prebiotics contained in the FBSPW because prebiotics can improve the protein and lipid metabolism functions of pigs [ 35 , 36 ].…”

Section: Discussionsupporting

confidence: 90%

Effects of Fermented Bamboo Shoot Processing Waste on Growth Performance, Serum Parameters, and Gut Microbiota of Weaned Piglets

Huang

Peng

Zheng

et al. 2022

Animals

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Gut microbiota (GM) plays a vital role in the nutrition and metabolism of weaned piglets. Some feed additives can be used to adjust the composition of GM to improve the health of weaned piglets. In this study, we investigated the effects of adding fermented bamboo shoot processing waste (FBSPW) to diet on growth performance, serum parameters, and GM of weaned piglets. Seventy-two piglets were divided into four groups and were fed diets containing 0% (control), 4% (group A), 8% (group B), and 12% (group C) FBSPW for 50 days. We found that the addition of FBSPW significantly decreased the average daily feed intake, serum triglyceride content, and urea nitrogen of weaned piglets compared to the control. The cecum and cecal microbiota of weaned piglets fed the basal diet with 12% FBSPW were significantly different compared to the control. A basal diet with 12% FBSPW significantly reduced the taxon feature number, and the relative abundance of Tenericutes in the cecum and cecal microbiota of weaned piglets compared with the control. The addition of 12% FBSPW to weaned piglet feed could improve their nitrogen and lipid metabolisms and have beneficial effects on GM.

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“…21 The presence of Lactobacillus in sufficient amounts is associated with decreasing cholesterol levels in serum in experimental animals. 22 Studies using in vitro, cell culture, and in vivo animals indicated probiotics can bind and prevent the absorption of aflatoxins, which have been demonstrated to be implicated in the etiology of liver cancer in humans, 23,24 a rat model of ethanol-induced liver damage, which has been used to demonstrate the protective effects of probiotics. 25 A recent review supported the use of probiotics in at least those patients with an end-stage kidney disease.…”

Section: Introductionmentioning

confidence: 99%

Protective effects of probioticLactobacillus plantarumBJ0021 on liver and kidney oxidative stress and apoptosis induced by endosulfan in pregnant rats

et al. 2015

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Endosulfan (EDS) is one of the most widely organochlorine insecticide used in many parts of the world, although it is currently banned or severely restricted in use in some countries. EDS causes a variety of negative effects in non-target species including humans. Therefore, the aim of the present study was to investigate the possible protective effects of Lactobacillus plantarum BJ0021 on toxicity, oxidative stress, and apoptosis induced by EDS intoxication on liver and kidneys of pregnant rats. This pesticide induced a significant increase in total cholesterol, alanine-amino transferase (ALAT), aspartate-amino transferase (ASAT), alkaline phosphatase (ALP), gamma-glutamyl transpeptidase (GGT), urea and creatinine in serum, while urinary urea and creatinine were lower than those of the control group. In the liver and kidney, lipid peroxidation increased significantly, the antioxidant levels, such as superoxide dismutase (SOD) and catalase (CAT) were markedly depressed and TdT-mediated dUTP-biotin Nick End Labeling (TUNEL) revealed more apoptotic cells. In contrast, co-administration of L. plantarum BJ0021 to EDS-treated animals ameliorated most of these biochemical parameters, but the activity of antioxidant enzymes (SOD, CAT) did not modify and the number of apoptotic nuclei remained significantly raised in kidney compared to control. In conclusion, the administration of L. plantarum BJ0021 decreased apoptosis and might play a protective role in reducing toxicity of EDS in pregnant rats.

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Hypocholesterolemic and Growth Promoting Effects of <i>Lactobacillus plantarum</i> AK Isolated from a Nigerian Fermented Cereal Product on Rats Fed High Fat Diet

Cited by 4 publications

References 21 publications

Hypolipidemic and hypoglycemic potential of raw, boiled, and sprouted mung beans (Vigna radiataL. Wilczek) in rats

Hypolipidemic and hypoglycemic potential of raw, boiled, and sprouted mung beans (Vigna radiataL. Wilczek) in rats

Effects of Fermented Bamboo Shoot Processing Waste on Growth Performance, Serum Parameters, and Gut Microbiota of Weaned Piglets

Protective effects of probioticLactobacillus plantarumBJ0021 on liver and kidney oxidative stress and apoptosis induced by endosulfan in pregnant rats

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