Hypnic headache in children

Cerminara, Caterina; Compagnone, Eliana; Coniglio, Antonella; Margiotta, Milena; Curatolo, Paolo; Villa, Maria Pia; Parisi, Pasquale

doi:10.1177/0333102411427601

Cited by 21 publications

(34 citation statements)

References 10 publications

(15 reference statements)

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“…Our results are consistent with this, except for one outlier in whom the onset of headaches was at age 44. Of note, some studies have reported HH in pediatric populations as well …”

Section: Clinical Characteristics and The Current Ichd‐3β Criteriasupporting

confidence: 84%

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Long‐Term Outcomes and Clinical Characteristics of Hypnic Headache Syndrome: 40 Patients Series From a Tertiary Referral Center

et al. 2016

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HH is an infrequent primary headache disorder that can present with cranial autonomic features. It can persist for years in the elderly. Lithium appeared to be the most effective treatment option, followed by caffeine at bedtime. Caffeine ingestion on awakening with an HH also demonstrated benefit. Cervicogenic headaches in the elderly and presence of active migraine are major confounders in the diagnosis of HHs.

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“…Our results are consistent with this, except for one outlier in whom the onset of headaches was at age 44. Of note, some studies have reported HH in pediatric populations as well …”

Section: Clinical Characteristics and The Current Ichd‐3β Criteriasupporting

confidence: 84%

“…Of note, some studies have reported HH in pediatric populations as well. 9,10 ICHD-3b's criteria for HH stipulate a minimum of 10 days/month frequency. All but 2 of our cases reported fewer than 10 days of HH a month.…”

Section: Clinical Characteristics and The Current Ichd-3b Criteriamentioning

confidence: 99%

Long‐Term Outcomes and Clinical Characteristics of Hypnic Headache Syndrome: 40 Patients Series From a Tertiary Referral Center

et al. 2016

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“…In one child, an initial dose of 2 mg nightly decreased headache intensity and frequency, and 4 mg rendered the patient asymptomatic. The other patient was treated with 3 mg melatonin nightly and also became headache‐free …”

Section: Hypnic Headachementioning

confidence: 99%

The Role of Melatonin in the Treatment of Primary Headache Disorders

Gelfand

Goadsby

2016

Headache

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Objective To provide a summary of knowledge about the use of melatonin in the treatment of primary headache disorders. Background Melatonin is secreted by the pineal gland; its production is regulated by the hypothalamus and increases during periods of darkness. Methods We undertook a narrative review of the literature on the role of melatonin in the treatment of primary headache disorders. Results There are randomized placebo-controlled trials examining melatonin for preventive treatment of migraine and cluster headache. For cluster headache, melatonin 10 mg was superior to placebo. For migraine, a randomized placebo-controlled trial of melatonin 3 mg (immediate release) was positive, though an underpowered trial of melatonin 2 mg (sustained release) was negative. Uncontrolled studies, case series, and case reports cover melatonin’s role in treating tension-type headache, hypnic headache, hemicrania continua, SUNCT/SUNA and primary stabbing headache. Conclusions Melatonin may be effective in treating several primary headache disorders, particularly cluster headache and migraine. Future research should focus on elucidating the underlying mechanisms of benefit of melatonin in different headache disorders, as well as clarifying optimal dosing and formulation.

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“…Women are affected more than men and the onset is usually after 50 years [53]. However, children with hypnic headache have been reported [54][55][56]. As per ICHD-III beta, headaches have to occur at least 10 days per month and last between 15 min and 4 h after waking [3••].…”

Section: Hypnic Headachementioning

confidence: 99%

Indomethacin-Responsive Headaches

VanderPluym

2014

Curr Neurol Neurosci Rep

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Indomethacin-responsive headaches are a heterogeneous group of primary headache disorders distinguished by their swift and often absolute response to indomethacin. The epidemiology of these conditions is incompletely defined. Traditionally, indomethacin-responsive headaches include a subset of trigeminal autonomic cephalalgias (paroxysmal hemicrania and hemicrania continua), Valsalva-induced headaches (cough headache, exercise headache, and sex headache), primary stabbing headache, and hypnic headache. These headache syndromes differ in extent of response to indomethacin, clinical features, and differential diagnoses. Neuroimaging is recommended to investigate for various organic causes that may mimic these headaches. Case reports of other primary headache disorders that also respond to indomethacin, such as cluster headache, nummular headache, and ophthalmoplegic migraine, have been described. These "novel" indomethacin-responsive headaches beg the question of what headache characteristics are required to qualify a headache as an indomethacin-responsive headache. Furthermore, they challenge the concept of using a therapeutic intervention as a diagnostic criterion.

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Hypnic headache in children

Abstract: Considering the very few cases of HH reported in paediatric age, our cases may expand the clinical spectrum of this disorder, suggesting a possible revision of the diagnostic criteria, with particular regard to the developmental age.

Cited by 21 publications

References 10 publications

Long‐Term Outcomes and Clinical Characteristics of Hypnic Headache Syndrome: 40 Patients Series From a Tertiary Referral Center

Long‐Term Outcomes and Clinical Characteristics of Hypnic Headache Syndrome: 40 Patients Series From a Tertiary Referral Center

The Role of Melatonin in the Treatment of Primary Headache Disorders

Indomethacin-Responsive Headaches

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