Hyperuricemia-associated Mesoamerican Nephropathy: Case Report and Review of Literature

Abstract

Mesoamerican nephropathy (MeN), formerly called chronic kidney disease of unknown cause (CKDu), refers to chronic kidney disease (CKD) that presents in young and middle-aged Central Americans in the absence of any clear etiology. MeN is a relatively new diagnosis with rapidly rising prevalence in specific regions of El Salvador and Nicaragua, Guatemala, and Costa Rica. It is seldom associated with hyperuricemia. We present a case of a patient with gouty arthritis and hyperuricemia with associated CKD due to MeN. We also provide a review of literature of this disease.

A rare complication of acute lower limb ischemia post coronavirus disease 2019 infection in a healthy pediatric patient: case report

“…However, after starting the management patient showed poor prognosis and had major amputations in which he died due to respiratory failure [ 11 ]. The patient, wherein we used a combination of Enoxaparin, tocilizumab, and pulse steroid therapy, later showed complete resolution of symptoms in all previously involved digits [ 12 ]. To our knowledge, this is the first report on the use of a combination of thrombolytic and anti-inflammatory therapy for treating COVID-19-induced ALI in pediatric patients reported in the international literature.…”