Hypertrichosis Portrayed in Art

Hypertrichosis terminalis, gingival hyperplasia, and a characteristic face: A new distinct entity

“…Hypertrichosis universalis or lanuginose congenital has been recognized as an autosomal dominant entity (OMIM *145700 [2000]) with several cases reported [Ravin and Hodge, 1969;Beighton, 1970;Freire-Maia et al, 1976;García-Cruz et al, 1997].…”

“…The lanuginose type has been mentioned above, with curly hair [Ravin and Hodge, 1969;Macías-Flores et al, 1984;García-Cruz et al, 1997], or with straight hair, as in the Ambras and Cantú syndromes [Cantú et al, 1982;Baumeister et al, 1993;García-Cruz et al, 1997;Balducci et al, 1998]. As indicated, hypertrichosis can be associated with gingival hyperplasia [Winter and Simpkiss, 1974;Bondeson and Miles, 1993] or with skeletal dysplasia, mental retardation, and cardiomegaly [Cantú et al, 1982].…”

“…As indicated, hypertrichosis can be associated with gingival hyperplasia [Winter and Simpkiss, 1974;Bondeson and Miles, 1993] or with skeletal dysplasia, mental retardation, and cardiomegaly [Cantú et al, 1982]. The facial features have been described in several reports as normal, [Ravin and Hodge, 1969;Freire-Maia et al, 1976], dysmorphic, in Ambras type [Baumeister, 1993;Balducci et al, 1998], or even coarse [Bondeson and Miles, 1993;Irvin et al, 1996].…”

Inherited hypertrichoses

“…The oldest cases of hypertrichosis known in the literature probably correspond to the family from d'Ambras Castle (16th century). A book published in 1742 entitled Aldrovandi Monstrorum Historia refers to an example of autosomal dominant inheritance in a family from the Canary Islands with four members covered by hair (5). In Austria, in 1853, Siebold discovered that the picture collection from d'Ambras' Castle (6) contained pictures of a hypertrichotic man, his normal wife, and his daughter and son both with hypertrichosis.…”

“…The children's heads were covered exactly like their father's, but Siebold mentions that the body of only one of his children was covered by hair (6). Two other daughters were similarly affected, and at least one of them passed on the condition to the next generation (5–8).…”