Hyperthymic temperament may protect against suicidal ideation

Vázquez, GH; Gonda, Xénia; Zaratiegui, Rodolfo; Lorenzo, Laura; Akiskal, Kareen K.; Akiskal, Hagop S.

doi:10.1016/j.jad.2010.04.015

Cited by 42 publications

(27 citation statements)

References 32 publications

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“…One study found that patients with higher hyperthymia and lower dysthymia scores had lower rates of white matter hyperintensities in the brain and had less risk for suicide than patients with lower hyperthymia and higher dysthymia scores (Serafini et al, 2011). Several other studies have found that hyperthymia appears to be protective against hopelessness (Pompili et al, 2008) and suicidality (Pompili et al, 2012; Rihmer et al, 2009; Vázquez et al, 2010). Rybakowski and colleagues (2013) recently reported a significant positive correlation between lithium response and hyperthymia.…”

Section: Discussionmentioning

confidence: 96%

Dimensional endophenotypes in bipolar disorder: Affective dysregulation and psychosis proneness

Mahon

Perez‐Rodriguez

Gunawardane

et al. 2013

Journal of Affective Disorders

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Background The clinical phenotype of bipolar disorder (BPD) is heterogeneous and the genetic architecture of the disorder is complex and not well understood. Given these complications, it is possible that the identification of intermediate phenotypes (“endophenotypes”) will be useful in elucidating the complex genetic mechanisms that result in the disorder. The examination of unaffected relatives is critical in determining whether a particular trait is genetically-relevant to BPD. However, few dimensional traits related to BPD have been assessed in unaffected relatives of patients. Methods We assessed affective temperament and schizotypy in 55 discordant sibling pairs and 113 healthy controls (HCs) using the Temperament Evaluation of Memphis, Pisa, Paris, and San Diego, Auto-questionnaire version (TEMPS-A) to assess affective temperament and the Schizotypal Personality Questionnaire (SPQ) to assess schizotypy. Results BPD patients scored significantly higher than HCs on all subscales of the SPQ and on all but one subscale (hyperthymic) of the TEMPS-A (all p <0.01). Siblings demonstrated scores that were significantly intermediate to patients and HCs on the anxious subscale of the TEMPS-A and on the interpersonal deficits and disorganized subscales of the SPQ. Limitations We did not investigate the BPD spectrum as most patients were diagnosed with BPD I (n = 47). Most of the patients had experienced psychosis (n = 42) and so we were unable to examine whether psychosis status impacted upon affective temperament or schizotypy in patients or their siblings. Conclusion These data suggest that schizotypy and affective temperament represent dimensional traits that are likely to underlie the genetic risk for BPD.

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Section: Discussionmentioning

confidence: 96%

Dimensional endophenotypes in bipolar disorder: Affective dysregulation and psychosis proneness

Mahon

Perez‐Rodriguez

Gunawardane

et al. 2013

Journal of Affective Disorders

View full text Add to dashboard Cite

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“…The few papers that have investigated affective temperament in patients with medical conditions did not examine the association between temperament and other psychological features. The protective role of hyperthymic temperament is probably due to a more effective coping strategy; indeed, coping strategy is known to play a crucial role in people's health, with major implications on both subjective and psychological well‐being…”

Section: Discussionmentioning

confidence: 99%

Suicidal ideation, perceived disability, hopelessness and affective temperaments in patients affected by Parkinson's disease

et al. 2018

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Summary Background Previous studies investigating the risk of suicide in patients with Parkinson's disease (PD) have reported conflicting results. This study evaluated suicide risk in PD and investigated the relationship between suicide risk and perceived disability, hopelessness and affective temperaments in PD. Methods One‐hundred and twenty PD patients were consecutively enrolled. The diagnosis of PD was based on clinical criteria. All patients underwent a psychiatric evaluation that included the administration of the Columbia‐Suicide Severity Rating Scale, the Italian Perceived Disability Scale, the Beck Hopelessness Inventory and the TEMPS‐A questionnaire. The results were compared with those of a control group of 91 patients affected by another chronic disease, ie, open angle glaucoma. Results Parkinson's disease patients had higher suicidal ideation, higher perceived disability and lower hyperthymia than the control group. In PD, higher perceived disability was associated with higher current and lifetime suicidal ideation, lower hyperthymia, older age and higher scores on negative temperaments. Suicidal ideation, negative temperaments and hopelessness were risk factors for perceived disability, while hyperthymia was a protective factor for perceived disability. Discussion Patients with PD have an increased risk of suicidal ideation. Increased suicidal ideation in PD is associated with the increased perceived disability. A psychiatric assessment that includes the investigation of suicide risk and perceived disability is recommended in patients with PD.

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“…[26]. Many studies have reported a relationship between temperaments and mental problems (e.g., suicide) [27, 28], mental status in non-clinical populations [29], depressive symptoms [30–32], mood disorders [33–37], anxiety disorders [38], alcohol abuse or dependence [39, 40], and substance abuse [41, 42]. In the workplace, a depressive temperament has been reported to be a kind of work-oriented personality [43], hyperthymic temperament has been reported to be a type of hyper-adapted personality [44].…”

Section: Introductionmentioning

confidence: 99%

Relationships between temperaments, occupational stress, and insomnia among Japanese workers

et al. 2017

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Insomnia among workers reduces the quality of life, contributes toward the economic burden of healthcare costs and losses in work performance. The relationship between occupational stress and insomnia has been reported in previous studies, but there has been little attention to temperament in occupational safety and health research. The aim of this study was to clarify the relationships between temperament, occupational stress, and insomnia. The subjects were 133 Japanese daytime local government employees. Temperament was assessed using the Temperament Evaluation of Memphis, Pisa, Paris, and San Diego-Auto questionnaire (TEMPS-A). Occupational stress was assessed using the Generic Job Stress Questionnaire (GJSQ). Insomnia was assessed using the Athens Insomnia Scale (AIS). Stepwise multiple logistic regression analyses were conducted. In a stepwise multivariate logistic regression analysis, it was found that the higher subdivided stress group by “role conflict” (OR = 5.29, 95% CI, 1.61–17.32) and anxious temperament score (OR = 1.33; 95% CI, 1.19–1.49) was associated with the presence of insomnia using an adjusted model, whereas other factors were excluded from the model. The study limitations were the sample size and the fact that only Japanese local government employees were surveyed. This study demonstrated the relationships between workers’ anxious temperament, role conflict, and insomnia. Recognizing one’s own anxious temperament would lead to self-insight, and the recognition of anxious temperament and reduction of role conflict by their supervisors or coworkers would reduce the prevalence of insomnia among workers in the workplace.

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Hyperthymic temperament may protect against suicidal ideation

Cited by 42 publications

References 32 publications

Dimensional endophenotypes in bipolar disorder: Affective dysregulation and psychosis proneness

Dimensional endophenotypes in bipolar disorder: Affective dysregulation and psychosis proneness

Suicidal ideation, perceived disability, hopelessness and affective temperaments in patients affected by Parkinson's disease

Relationships between temperaments, occupational stress, and insomnia among Japanese workers

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