Hypertensive disorders of pregnancy and risk of asthma and chronic obstructive pulmonary disease: a prospective cohort study

Wang, Yi‐Xin; Varraso, Raphäelle; Dumas, Orianne; Stuart, Jennifer; Florio, Andrea A.; Wang, Liang; Rich‐Edwards, Janet W.; Camargo, Carlos A.; Chavarro, Jorge E.

doi:10.1016/j.lana.2023.100540

Cited by 1 publication

(2 citation statements)

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“…14 Furthermore, research published in the Lancet Regional Health revealed that pregnant women with hypertensive disorders have an increased risk of developing asthma and chronic obstructive pulmonary diseases. 15 Moreover, pre-eclampsia and eclampsia made a substantial contribution to maternal deaths and severe morbidity. 4 16 10% to 15% of all maternal deaths worldwide are attributed to pre-eclampsia and eclampsia.…”

Section: Strengths and Limitations Of This Studymentioning

confidence: 99%

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Maternal outcomes of pre-eclampsia with severe features and its determinants at Abebech Gobena Mothers and Childrens Health and Saint Peter’s Specialized Hospital, Addis Ababa, Ethiopia: a cross-sectional study

Tadese,

Damesa,

Solomon

et al. 2024

BMJ Open

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ObjectiveThe main objective of this study was to determine the prevalence and factors associated with unfavourable maternal outcomes among pregnant women with pre-eclampsia with severity features (PEWSF) at Abebech Gobena Maternal and Children’s Health and St. Peter’s Hospital, Addis Ababa, Ethiopia, 2023.DesignA hospital-based cross-sectional study was conducted from 1 January 2023 to July 2023. The data was collected using a structured and pre-tested questionnaire through face-to-face interviews and a review clinical chart. Data was entered using EpiData V.4.6 and analysed using SPSS V.26.0 statistical software. Binary logistic regression analysis was run to identify predictors of maternal outcome.SettingTwo hospitals in Addis Ababa, Ethiopia.Participants348 pregnant women with PEWSF were included.Outcome measuresUnfavourable maternal outcome was defined as mothers with PEWSF that develop at least one complication, that is, eclampsia, abruption placenta, Haemolysis, Elevated Liver Enzymes and Low Platelet Count (HELLP) syndrome, acute renal failure, disseminated intravascular coagulation, cardiac failure, stroke, postpartum haemorrhage, pulmonary oedema and death.ResultsThe overall prevalence of unfavourable maternal outcomes was 33.9% (N=118) (95% CI=28.7 to 38.8). Abruptio placenta (17.2%), HELLP syndrome (15.5%) and postpartum haemorrhage (13.8%) were common complications that occurred among mothers with PEWSF. Age above 35 years (adjusted OR (AOR) (95% CI)=2.70 (1.31 to 5.59)), rural residence (AOR (95% CI)=1.94 (1.07 to 3.53)), unemployment (AOR (95% CI)=0.35 (0.20 to 0.62)), severe blood pressure on admission (AOR (95% CI)=2.32 (1.03 to 5.19)) and complain of severe headache (AOR (95% CI)=1.91 (1.16 to 3.16)) were significant associates of unfavourable maternal outcomes.ConclusionsThe prevalence of unfavourable maternal outcomes was high compared with other studies in Ethiopia. Maternal age, residence, occupation, blood pressure on admission and severe headache have shown a statistically significant association with unfavourable maternal outcomes. Socioeconomic development and early identification of severe signs and symptoms of pre-eclampsia are needed to reduce unfavourable outcomes.

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Section: Strengths and Limitations Of This Studymentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%