Hypertensive disorders in pregnancy: screening by uterine artery Doppler imaging and blood pressure at 11–13 weeks

Abstract

Objectives To examine the performance of screening for hypertensive disorders in pregnancy at [11][12][13]

Hypertensive disorders in pregnancy: combined screening by uterine artery Doppler, blood pressure and serum PAPP‐A at 11–13 weeks

“…The estimated detection rates for early PE, late PE and GH are about 37, 30 and 20%, respectively, at a 5% false-positive rate (Poon et al, 2009a). We have also demonstrated that the combination of maternal factors with biophysical tests comprising mean arterial pressure (MAP) and uterine artery pulsatility index (PI) recorded from the artery with the lowest PI (L-PI) further improved the detection rates of early PE, late PE and GH to 78, 42 and 36%, respectively, at a 5% false-positive rate (Poon et al, 2009b).…”

The diagnostic accuracy of the usage of the <i>Fetal Medicine Foundation</i>’s (FMF) on-line risk calculator with first-trimester ultrasound for screening for preeclampsia in high-risk pregnant Brazilian population

“…Most of the studies concerning this subject are dated after 2009 [4,[18][19][20]24]. Maternal characteristics associated with biochemical and biophysical tests at 11 -13 weeks' gestation can identify 90%, 80% and 60% of pregnancies that will result in early, intermediate and late PE, respectively [4].…”

“…We also considered maternal clinical variables (e.g., age, ethnicity, weight, height, body mass index, mode of conception, smoking history, illicit drug use, history of hypertension, history of diabetes and history of systemic lupus erythematous), obstetrical variables (e.g., parity, history of PE in the woman's mother, history of previous PE, history of miscarriages and stillbirths), ultrasound data (e.g., fetal crown-rump length and pulsatility index of uterine arteries) and blood pressure (BP) measured at the time of examination [13,[17][18][19][20][21][22]. No maternal serum biochemical markers were used in the risk assessment for pre-eclampsia; only the clinical information, obstetric ultrasound and BP measurements were used.…”

“…Many current studies have demonstrated the possibility of pre-eclampsia screening between 11 and 13 weeks with promising results [4,13,[16][17][18][19][20][21][22]. This screening focuses on the multivariate analysis of risk associating maternal data, clinical, obstetric, ultrasound and serum marker measurements [19,20].…”

Etiopathogenesis of hypertension in pregnant women

“…Poon i wsp. [39,54,55] kilkukrotnie wykazali, że MAP ma dużą wartość predykcyjną stanu przedrzucawkowego. Doniesienia te potwierdzili też inni badacze [56].…”