Hypertension Produced by Unilateral Renal Disease

Difficulties in the Evaluation of Hypertension Secondary to Renal Ischemia

“…Large areas of ischemic tissue excreting little or no urine can be detected by grossly disproportionate reductions in urine flow in relation to smaller discrepancies in renal mass. H o w a r d and C o n n o r [10] noted, 'in these situations a significant difference exists in urine volumes, but the chemical composition from the 2 sides is nearly identical'. These authors made no correlation be tween the disparity in renal size and urine volume.…”

Experience with radiology in the diagnosis of renal hypertension

“…Using standard techniques and even with experienced observers interpreting the radiographs there may be no abnormality in 25 per cent or more cases of renal artery stenosis as compared with perhaps 10 per cent of false negatives in isotope renography (Howard and Connor, 1962; Morris and De Bakey, 1962). The routine use of minute sequence films for estimating excretion rate and urea infusion diuresis techniques may increase the diagnostic accuracy (Amplatz, 1964).…”

Reno vascular Hypertension in Children

“…The isotopic renogram dis closes findings similar to those of a good uro gram, therefore it is not systematically em ployed. Due to technical difficulties, risks of infection, and to the imprecision of the ob tained data, we do not routinely perform the split-function test proposed by Howard and Connor (8), in pediatric patients (17,30). The arteriogram, despite being a more aggressive procedure, gives more precise information re garding the site, type, laterality and extension of the vascular lesion, and, in experienced hands, has a small incidence of accidents (23).…”