Hypertension and Related Risk Factors among Clients on Combined Antiretroviral Therapy in Nigeria

Bello, Surajudeen Oyeleke; Ojieabu, Winified A

doi:10.21065/1920-4159.1000252

Cited by 1 publication

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References 16 publications

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“…The Human Immunodeficiency Virus (HIV) poses a significant global public health threat, with its increasing association with cardiovascular complications, cerebral-vascular incidents, and vasculopathy over the past two decades. 1 These HIV-related complications contribute to elevated mortality and morbidity rates in both developed and developing countries. 2 , 3 Hypertension, a top contributor to cardiovascular diseases and a global leading cause of death, is notably prevalent among individuals with diabetes, with over 45% of diabetic patients succumbing to complications related to hypertension.…”

Section: Introductionmentioning

confidence: 99%

Prevalence and Factors Associated with Hypertension Among HIV Positive Patients on Antiretroviral Therapy: A Hospital-Based Cross-Sectional Study in Rwanda

Uwanyirigira,

Biracyaza,

Uzabakiriho

et al. 2023

VHRM

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The human immunodeficiency virus (HIV) and the use of antiretroviral therapy (ART) are influential elements contributing to hypertension, which is a public health concern particularly in sub-Saharan Africa where its underdiagnosis and limited investigation persist. Moreover, hypertension prevails at higher rates among individuals living with HIV (PLWH) in comparison to the general population. Therefore, our study determined the prevalence of hypertension and its associated factors among PLWH who are undergoing ART treatment at Byumba District Hospital. Methods: A cross-sectional study design was conducted among 406 PLWH over the age of 14 years who were undergoing ART within the HIV department. We performed statistical analyses using STATA version 13. Significant independent variables identified in the bivariate analysis were further exported in a multivariable logistic regression model to ascertain their association with hypertension. This model elucidated factors associated with hypertension, presenting outcomes through odds ratios and their respective 95% confidence intervals, with statistical significance set at p < 0.05. Results: The prevalence of hypertension was 24.7%, which means that roughly 1 in 4 PLWH were hypertensive. Notably, individuals aged 41 years and above demonstrated a significant association with heightened hypertension [AOR = 4.49; 95% CI = 2.45-8.21, p < 0.001] in contrast to those aged between 14 and 40 years. Additionally, smokers [AOR = 12.12; 95% CI = 4.48-32.74, p < 0.001] and individuals with a family history of hypertension [AOR = 4.28; 95% CI = 1.01-18.13, p = 0.049] demonstrated a higher likelihood of hypertension than their counterparts. Moreover, alcohol consumers [AOR = 5.5; 95% CI = 2.75-10.9, p < 0.001] had an increased likelihoods of hypertension compared to non-drinkers. Lastly, diabetics were almost 6 times more likely to be hypotensive [AOR = 4.50; 95% CI = 2.55-7.95, p = 0.018] when compared to those without diabetes. Conclusion: Our findings strongly underscore the urgency for the implementation of targeted programs aimed at enhancing awareness and comprehension of the factors and potential complications tied to hypertension among PLWH. Such programs could be integrated into routine HIV care services to provide patients with the information and skills required to manage their hypertension effectively.

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Section: Introductionmentioning

confidence: 99%