Hypertension and elevated heart rate

Tomlinson, Brian; Sritara, Piyamitr; Lopez, Eleanor; Dalal, Jamshed; Erwinanto, Erwinanto; Pancholia, Arvind K.

doi:10.1097/hjh.0000000000001125

Cited by 4 publications

(4 citation statements)

References 24 publications

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“…[ 30 ] The increased sympathetic tone also causes an increase in cardiac output, meanwhile provides sustained pulsatile stress to the blood vessels, which will lead to an increased arterial stiffening and arterial hypertension. [ 17 , 32 ] But these explanations were mostly applied to adults. Notwithstanding, the relationship between arterial stiffness and BP variability in children and adolescents has also been demonstrated, detailed mechanism in children needs to be explored by further research.…”

Section: Discussionmentioning

confidence: 99%

“…[ 15 , 16 ] The relationship between RHR/RPR and hypertension has also been established among adults and children in numbers of cross-sectional studies. [ 17 – 22 ] Meanwhile, limited prospective studies conducted in adults have also demonstrated the association between increased RHR/RPR and high risk of hypertension development. [ 23 , 24 ] In Kailuan cohort study including 31,507 participants, Wang et al [ 23 ] examined the association between RHR and new-onset hypertension.…”

Section: Introductionmentioning

confidence: 99%

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Association of elevated resting pulse rate with increased risk of hypertension development in children

Shen

Chu³

et al. 2017

Medicine

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Background:Elevated resting heart rate (RHR) or resting pulse rate (RPR) is associated with increased risk of hypertension development. However, information is limited to adults. The purpose of this study is to analyze this association among Chinese children in a prospective design.Methods:A total of 4861 children who participated in the Blood Pressure Surveillance Program (2011–2017) were selected in this research. To investigate the association between RPR and hypertension development, children were divided into 4 groups according to the quartiles of RPR at baseline. Odds ratios (ORs) with 95% confidence intervals (CIs) were calculated using logistic regression model.Results:Over a mean follow-up of 3.0 ± 0.1 years, there were 384 cases of incident hypertension. Compared to boys and girls in the 1st quartile, those in the 4th quartile were 1.73 (95% CI 1.13, 2.65), 2.22 (95% CI 1.43, 3.45) times more likely to have hypertension, respectively. Every 10 bpm increase in RPR was associated with a 26% greater risk of hypertension development in boys (OR: 1.26; 95% CI 1.10, 1.44), while this risk was 1.28 (95% CI 1.13, 1.44) in girls. Baseline blood pressure (BP) and body mass index (BMI) did not have significant interactions with RPR on risk of hypertension development.Conclusion:This study confirms the relationship between elevated RPR and increased risk of hypertension development in children, independent of confounders including baseline BP and BMI. An elevated RPR could be considered as a risk factor for the assessment of hypertension, no matter from a clinical setting or a public health perspective.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Association of elevated resting pulse rate with increased risk of hypertension development in children

Shen

Chu³

et al. 2017

Medicine

View full text Add to dashboard Cite

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“…Different from previous studies which analyzed the BMI or BMI Z scores as continuous variable, [13][14][15][16] the transition between normal weight and overweight during school age was analyzed in the present study. With longitudinal follow-up data collected from 2005 to 2016, we analyzed the overweight risk transition from age of 7 to 18 years, and intended to investigate (1) the pattern of children's overweight risk development during childhood; (2) the associations between the change in overweight risk and their blood pressure outcomes at late adolescence.…”

mentioning

confidence: 99%

“…Hypertension has become one of the major health problems in most Asian countries, which led to a dramatic increase in disability-adjusted life-years. 1,2 A global trend of the growing incidence of childhood hypertension was observed during the past 2 decades, which called an alert for early intervention in the high-risk population. 3 Therefore, it is of great importance to make appropriate investigations and interventions to the high-risk pediatric population to reduce the disease burden that may occur in the future.…”

mentioning

confidence: 99%

Exploring Overweight Risk Trajectories During Childhood and Their Associations With Elevated Blood Pressure at Late Adolescence: a Retrospective Cohort Study

Wang

Huang³

et al. 2022

Hypertension

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Background: Overweight during childhood is significantly associated with higher risk of high blood pressure (HBP) in later life. However, recognition of critical intervention period is limited. We aimed to analyze the changes in overweight risk during school-age and its relationship with HBP. Methods: Seventeen thousand eight hundred sixteen school-aged children (53.9% boys) with a mean follow-up time of 8.2 years were involved. Children’s overweight was defined as body mass index Z score ≥1 and was fitted with a group-based trajectory model. The 4 trajectories were labeled as constant low, high decreasing, low rising, and constant high according to the change of overweight risk during follow-up. Population-averaged logit model and log-binomial regression models were used to analyze HBP risk. Cox proportional hazard model was used to analyze the HBP incidence among distinct groups. Results: Children with higher overweight risk generally had higher HBP risk during follow-up. However, the HBP risk in low rising group was low at baseline and increased to 3.14 (95% CI, 2.54–3.88; P <0.001) for boys and 3.23 (95% CI, 2.08–5.01; P =0.004) for girls at end point, which were comparable to the relative risk in the constant high group (4.60 [95% CI, 4.02–5.27] for boys and 5.28 [95% CI, 3.94–7.07] for girls). Conclusions: Findings of this study provide insights on patterns of overweight risks during childhood. Children with transition from normal to overweight during teen years would be high-risk in HBP incidence.

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Liraglutide for weight management: benefits and risks

Tomlinson

Zhang

et al. 2017

Current Medical Research and Opinion

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Hypertension and elevated heart rate

Cited by 4 publications

References 24 publications

Association of elevated resting pulse rate with increased risk of hypertension development in children

Association of elevated resting pulse rate with increased risk of hypertension development in children

Exploring Overweight Risk Trajectories During Childhood and Their Associations With Elevated Blood Pressure at Late Adolescence: a Retrospective Cohort Study

Liraglutide for weight management: benefits and risks

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