“…Effective mathematical modelling serves as a valuable tool for elucidating enzymatic reaction processes. Since direct analytical solutions are unavailable for many non-linear enzymatic reaction equations, employing approximate analytical methods such as the variational iteration method (VIM) [4,5], Akbari Ganji method (AGM) [6,7], differential transform method (DTM) [8,9], homotopy perturbation method (HPM) [10,11], and homotopy analysis method (HAM) [12,13] becomes essential for obtaining analytical solutions. Most realistic models across chemistry, engineering, biology, and physics exhibit nonlinearity, making obtaining analytical solutions for such systems impractical.…”