Hypersensitivity Reactions Following Onabotulinum Toxin A Touch-up Injection Possibly Associated with Covid-19 Infection

Li, Yiming; Jiang, Qinqin; Wang, Hui; Wang, Xiang

doi:10.1007/s00266-023-03584-9

Cited by 3 publications

(3 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…All allergic symptoms listed in Supplemental Digital Content 1 (http://links. lww.com/PRSGO/D233 7,[9][10][11][12][14][15][16][17][18][19]21,[23][24][25]31 ) could be alleviated with corticosteroids. However, there have been no articles reporting allergic symptoms occurring in other sites instead of the injection sites so far.…”

Section: Discussionmentioning

confidence: 99%

“…Balighi et al 10 reported a case of delayed-type BTA allergy and granulomatous inflammation that occurred 11 months after the patient received BTA injection. All allergic symptoms listed in Supplemental Digital Content 1 (http://links.lww.com/PRSGO/D233 7,9–12,14–19,21,23–25,31 ) could be alleviated with corticosteroids. However, there have been no articles reporting allergic symptoms occurring in other sites instead of the injection sites so far.…”

Section: Discussionmentioning

confidence: 99%

“…A literature review including 15 case reports and one clinical trial was conducted, including a total of 20 cases and one double-blind trial (Supplemental Digital Content 1, http://links.lww.com/PRSGO/D233). The most common symptoms include swelling and edema 9,11,12,[14][15][16][17][18][19]24 (11 of 20, 55%), erythema [9][10][11]14,16,19,20 (six of 20, 30%), rash 10,15,19,21,31 (six of 20, 30%), pruritus 9,15,18,19,31 (seven of 20, 35%), and granulomatous inflammation 7,10,31 (four of 20, 20%). Guo et al 12 reported two cases of severe and subacute hypersensitive reaction that occurred in patients with a history of corona virus 2019 vaccination but with no BTA allergic history.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Mild Allergic Reactions after Botulinum Toxin Injection: A Case Series and Literature Review

Li,

Zheng,

Lin

et al. 2024

Plastic and Reconstructive Surgery - Global Open

View full text Add to dashboard Cite

Background: Botulinum toxin type A (BTA) is becoming more and more prevalent as an injection agent in cosmetic surgery. However, there is an increasing amount of cases reporting unexpected adverse reactions related to BTA injection. BTA can invoke many kinds of hypersensitive reactions, some of which can be delayed-type or even fatal; hence, it is of crucial importance to pay close attention to atypical and early symptoms that may indicate the presence of BTA allergy in patients. Methods: In this study, we reported three cases of mild and unexpected BTA-related hypersensitive reaction with a symptom of nonpruritic erythema on the chest that happened after BTA treatment of upper facial wrinkles and proposed several suggestions based on our practical experience and literature review. Results: Two patients’ symptoms were alleviated spontaneously, and one patient’s were alleviated after taking oral corticosteroid. According to our literature review, we believe that these incidences indicate a kind of unreported allergic reaction relevant to botulinum toxin. Conclusions: We suggest clinicians consider warily patients’ subsequent BTA injection schedule if any suspicious reaction occurs after treatment. We suggest that patients who experience nonpruritic erythema after botulinum toxin injection should suspend subsequent injection plans for at least 3 months to prevent more severe consequences.

show abstract