Hyperpigmentation and melasma

Rigopoulos, Dimitrios; Gregoriou, Stamatis; Katsambas, A.

doi:10.1111/j.1473-2165.2007.00321.x

Cited by 133 publications

(108 citation statements)

References 59 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…[65][66][67]69 Embora a afecção tenha uma conotação, muitas vezes, somente do ponto de vista estético, com tal preocupação, pode ser muito importante e impactante na vida social, familiar e profissional dos indivíduos acometidos, provocando efeitos psicológicos que não podem ser negligenciados. 65,73 Em 2003, o MELASQoL, um novo instrumento de qualidade de vida relacionado à saúde para mulheres com melasma, foi publicado por Balkrishnan e colaboradores. Tal instrumento foi validado e demonstrou utilidade para monitorar o impacto, causado pelo melasma, na qualidade de vida dos pacientes.…”

Section: Melasmaunclassified

Fisiopatologia do melasma

Miot¹,

Miot²,

Silva³

et al. 2009

An. Bras. Dermatol.

121

View full text Add to dashboard Cite

Resumo: Melasma é uma dermatose comum que cursa com alteração da cor da pele normal, resultante da hiperatividade melanocítica focal epidérmica de clones de melanócitos hiperfuncionantes, com consequente hiperpigmentação melânica induzida, principalmente, pela radiação ultravioleta. Clinicamente, caracteriza-se por manchas acastanhadas, localizadas preferencialmente na face, embora possa acometer também região cervical, torácica anterior e membros superiores. Mulheres em período fértil e de fototipos intermediários representam as populações mais acometidas. Grande parte de sua fisiopatogenia permanece desconhecida, havendo relação com fatores genéticos, hormonais, uso de medicamentos, cosméticos, endocrinopatias e fotoexposição. Os autores discutem os principais elementos relacionados à pigmentação da pele e ao desenvolvimento do melasma. Palavras-chave: Melanose; Pigmentação da pele; Raios Ultravioleta; Transtornos da pigmentação Abstract: Melasma is a common dermatosis that involves changes in normal skin pigmentation, resulting from the hyperactivity of epidermal melanocytes. The consequent hyperpigmentation is mostly induced by ultraviolet radiation. Clinically, melasma is characterized by light to dark brown macules that usually occur on the face, although they can also affect the cervical and anterior thoracic regions and upper members. Fertile age women and those with intermediate skin phototypes are most likely to develop melasma. Most of its physiopathogenics is not yet fully understood, but there is a relation with genetic and hormonal factors, drugs and cosmetics use, endocrinopathies and sun exposure. The authors discuss the main aspects associated with skin pigmentation and the development of melasma.

show abstract

Section: Melasmaunclassified

Fisiopatologia do melasma

Miot¹,

Miot²,

Silva³

et al. 2009

An. Bras. Dermatol.

121

View full text Add to dashboard Cite

show abstract

“…In fact, PODC can be a combination of the abovementioned factors [4] .On the other hand, it has been suggested that cutaneous hyperchromia of the orbital region is not associated with underlying diseases in many cases, as it can affect completely normal people [5] . Available treatments for PODC include topical bleaching agents, chemical peeling, carboxytherapy, laser therapy, injectable fillers, autologous fat transplantation and surgery (blepharoplasty) [6,7] . Chemical peeling is considered as a simple in-office technique.…”

Section: Introductionmentioning

confidence: 99%

Treatment of Periorbital dark circles: Comparative study of chemical peeling with a combination of trichloroacetic acid and lactic acid versus carboxytherapy

Hassan¹,

Aldalies²,

Maghraby³

2016

J Surg Dermatol

View full text Add to dashboard Cite

Periorbital dark circles (PODC) are a common worldwide cosmetic problem. It is difficult to treat due to complications in its pathogenesis and aetiology. Available lines of treatment for PODC include whitening creams, topical retinoid acid, chemical peeling, laser therapy, carboxytherapy, autologous fat transplantation, injectable fillers and surgery (blepharoplasty).The aim of this study isto evaluate and compare the efficacy of chemical peels using trichloroacetic acid (3.75%) and lactic acid (15%) in a gel formula with that of carboxytherapy, in the treatment of periorbital hyperpigmentation.Two groups of patients with PODC were included in the study, named Group A and B in which each group consisted of 15 patients. Group A was assigned for patients who received treatment with chemical peeling with a combination of trichloroacetic acid (3.75%) and lactic acid (15%) in a gel formula, once a week for four weeks. Group B was assigned for patients who received carboxytherapy that was performed by subcutaneous and intradermal injection of CO 2 once a week for four weeks. All patients were assessed by digital photographs, before and after treatment, by observing the improvement in the grade of PODC. Reports of patient satisfaction and global tolerance were evaluated by three medical observers. There was a significant improvement in the grade of PODC in both groups. The degree of improvement of PODC in group A was excellent, with good grade in 93.4% of the treated patients while fair grade in 6.6% of them. There was a statistically significant improvement in the pigmented type. The degree of improvement of PODC in group B was excellent, with good grade in 86.7% of the treated patients while fair grade in 13.3% of them. However, no statistically significant difference between the two groups was observed. Minimal and transient side effects were noticed; however, it did not require further treatment. In conclusion, the two methods of treatment were effective in the treatment of PODC, with the improvement of PODC observed from the first treatment session with both chemical peeling and carboxytherapy.

show abstract

“…Gazelle eye like facial melanosis although is not un common pigmentory problems among Iraqi population but unfortunately often confused and mixed up either with melasma especially dermal type [1][2][3][4][5][6][7][8][9][10][11][12][13] or with frictional melanosis [13][14][15].…”

Section: Discussionmentioning

confidence: 99%

“…The skin is darkly pigmented thickened In addition there is not uncommon facial pigmentation that is locally known as Gazelle eye like facial melanosis that is commonly encountered in clinical practice but often misdiagnosed and commonly confused with melasma and does not respond to ordinary therapy options for melasma [1][2][3]6,[8][9][10][11][12][13][14].…”

Section: -Frictional Melanosismentioning

confidence: 99%

“…It could be defined as chronic disfiguring dermatological disease of females and males ,although much more common among females that appear during the active reproductive period with the presence of provoking factors like hormonal changes and sunlight that induce brown hyperpigmentation of the face .This may take many shapes but much more commonly a butterfly and a mask appearance [6][7][8][9][10][11][12][13].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation