Abstract:Abstract. The role of the kidney in states of hyperoxaluria and hypercalciuria was investigated in seven patients with hyperoxaluria after jejunoileal bypass (JIB) and six patients with idiopathic hypercalciuria (IHC). Eight apparently healthy persons formed a control group.Besides hyperoxaluria, the patients with JIB displayed an elevated plasma concentration of oxalate and the oxalate clearance was increased and higher than creatinine clearance, indicating a net tubular secretion of oxalate. The JIB patients… Show more
“…It has also been noted that tubular oxalate secretion is increased in PH patients possibly in an attempt to mitigate the life threatening consequences of systemic oxalosis [21] . Increased tubular secretion has also been noted in patients with hyperoxaluria following intestinal bypass [22] .…”
Hyperoxaluria is characterized by an increased urinary excretion of oxalate. Primary and secondary hyperoxaluria are two distinct clinical expressions of hyperoxaluria. Primary hyperoxaluria is an inherited error of metabolism
“…It has also been noted that tubular oxalate secretion is increased in PH patients possibly in an attempt to mitigate the life threatening consequences of systemic oxalosis [21] . Increased tubular secretion has also been noted in patients with hyperoxaluria following intestinal bypass [22] .…”
Hyperoxaluria is characterized by an increased urinary excretion of oxalate. Primary and secondary hyperoxaluria are two distinct clinical expressions of hyperoxaluria. Primary hyperoxaluria is an inherited error of metabolism
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