Objectives: Intended meanings in verbal irony differ from those of the actual words. To look behind these words, we need to integrate perspectives of ourselves, others, and their beliefs about us. Although patients with borderline personality disorder (BPD) experience problems in social cognition and schizotypal symptoms, research on irony comprehension mainly focused on the latter. Accounting for possible negative biases in BPD, the current study examined the detection of praising and critical irony in a text message interface. Design: A cross-sectional study including 30 patients and 30 matched healthy controls (HC).Methods: Participants completed measures of cognitive and affective empathy (Interpersonal Reactivity Index, IRI), schizotypal (Schizotypal Personality Questionnaire; SPQ), and borderline symptoms (Borderline Symptom List; BSL-23). Asking for literality and intention ratings of the stimuli, the paradigm allowed to analyze literality detection, implicit and explicit response biases in a signal detection framework.Results: Borderline symptoms explained decreased sensitivity for the detection of literal and ironic statements across groups. While HC showed a negativity bias on an implicit level, BPD perceived praising remarks less praising when explicitly asked, but no difference on critical remarks. Neither empathy, nor schizotypy explained any outcomes. Conclusion: This was the first study to show impaired detection of verbal irony in patients with BPD. While patients were less biased than HC in implicit measurements, they perceived praising remarks as less positive. Results stress the potential resource of non-verbal therapies to establish an appreciating therapeutical environment and contribute to difficulties in self-other distinction in BPD.