Hyperlipidemia and pancreatitis

Buch, Annette; Buch, J; Carlsen, Agnete; Schmidt, Arne

doi:10.1007/bf02393387

Cited by 46 publications

(18 citation statements)

References 30 publications

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“…Since first documented by Speck in 1846 [1] , the aetiopathogenic relationships of abnormalities of lipid metabolism to pancreatitis remain unclear [2][3][4] . Primary lipid disorders, especially those with triglycerides above 11.3 m M , cause episodes of acute pancreatitis [5] .…”

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confidence: 99%

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Dyslipidaemic Pancreatitis Clinical Assessment and Analysis of Disease Severity and Outcomes

et al. 2009

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Introduction: The relationship between pancreatitis and dyslipidaemia is unclear. Patients and Methods: Admissions with acute pancreatitis were prospectively evaluated. A comparison of the demographic profile, aetiology, disease severity scores, complications and deaths was made in relationship to the lipid profiles. Results: From June 2001 to May 2005, there were 230 admissions. The pancreatitis was associated with alcohol (63%), gallstones (18%), idiopathic (9%) and isolated dyslipidaemia (10%). Dyslipidaemia was significantly different between the two predominant race groups: Indian 50.5% and African 17.9% (p < 0.000017). Seventy-eight (34%) had associated dyslipidaemia and 152 (66%) were normolipaemic at admission. The average body mass index was higher in the dyslipidaemic group (27 ± 6) than in the normolipaemic group (24.5 ± 6.20; p = 0.004). The mortality rate was similar between the dyslipidaemic and normolipaemic patients (10 and 8%, respectively) and unrelated to race (p = 0.58). The 9 deaths in the dyslipidaemic group occurred in those with persistent hypertriglyceridaemia irrespective of its level (p = 0.003). Conclusion: Dyslipidaemic pancreatitis was more common in the Indian ethnic group. Adverse outcomes in those with dyslipidaemia were predominantly associated with hypertriglyceridaemia.

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Section: Introductionmentioning

confidence: 99%

“…The prevalence of lipid abnormality in pancreatitis varies from 3.8 to 39%, depending on whether levels are routinely or selectively measured [3,4,13,14] . It is unclear whether dyslipidaemia alters the outcomes of pancreatitis.…”

Section: Introductionmentioning

confidence: 99%

Dyslipidaemic Pancreatitis Clinical Assessment and Analysis of Disease Severity and Outcomes

et al. 2009

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“…This process is, however, not completely understood. Hyperlipemia is an accompanying condition in AP accounting from 1.5 to 53% of the cases [6][7][8][9]. It is not known, however, whether it is a cause or an effect of acute pancreatitis.…”

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confidence: 99%

Serum Free Fatty Acid Concentration in Patients with Acute Pancreatitis

Sztefko

Panek

2001

Pancreatology

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“…We report a retrospective study of patients with acute pancreatitis who were admit1ed to the Riyadh Armed Forces Hospital over a 40 month period to show the relatively low incidence of alcoholism as an etjologic factor. (7), acute renal failure (3), and pulmonary complications (2). Two of these patieflls died.…”

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Acute Pancreatitis in an Alcohol Prohibited Society

Hanid¹,

Al-Karawi²,

Mohamed³

1989

J Islam Med Assoc

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of investigations, e.g., sonography, cholecystogram, lipid profile, endoscopic retrograde cholangiopancreatography (ERCP) outcome, surgical treatment, and complications. An attempt to define the etiology was made. ResultsTwenty-three cases of acute pancreatitis (0.03070) were admitted over this 40 month period. These were composed of 16 females (age range 12-79 ye~rs, mean 51.8 years) and 7 males (age range 7-59 years, mean 42.3 years). In all cases, the presentation was acute with abdominal pain, nausea, and vomiting. In all instances the serum amylase was over 600 lUlL (normal range = 0-100 lUlL). In 21 out of 23 cases, the level was greater than 1,000 lUlL. The diagnostic tests and etiology are shown in Tables 1 and 2, respectively.The presence of gallstones was confirmed in nine patients, in one of which the pancreatitis occurred two days post-cholecystechtomy, and cholelithiasis was believed to be the causative factor. In three patients, hyperlipidemia was considered to be the predisposing factor. These three patients were known to have hyperHpidemia before their presentation with acute pancreatitis. A seven ye.ar old child presented with acute pancreatitis due to a mumps infection and one patient had a hydatid cyst obstructing the lower The exact cause of acute pancreatitis is uncertain in some patients. However, there are certain well documented predisposing causes such as alcoholism, 1 hyperlipidemia,2 hypercalcemia. J biliary tract disease ... • trauma,6 and familial inheritance.7 Within the Kingdom of Saudi Arabia, alcohol consumption is prohibited. We report a retrospective study of patients with acute pancreatitis who were admit1ed to the Riyadh Armed Forces Hospital over a 40 month period to show the relatively low incidence of alcoholism as an etjologic factor.

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Hyperlipidemia and pancreatitis

Cited by 46 publications

References 30 publications

Dyslipidaemic Pancreatitis Clinical Assessment and Analysis of Disease Severity and Outcomes

Dyslipidaemic Pancreatitis Clinical Assessment and Analysis of Disease Severity and Outcomes

Serum Free Fatty Acid Concentration in Patients with Acute Pancreatitis

Acute Pancreatitis in an Alcohol Prohibited Society

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