Hyperkalemia and ion exchange resins—limitations

Abstract

A clinical observation of hyperkalemia in a dialyzed patient operated on 3 times following a perforated colic diverticula, led us to discuss the action site of a cation exchange resin. Other therapeutic possibilities to manage hyperkalemia in a non‐dialytic fashion in end‐stage renal disease patients are reviewed. Such situations are rare, but may occur again.

Cyclodextrin Polymers Functionalized with Histidine and Carcinine as Chelating Therapeutics for Copper Dyshomeostasis

“…[15] Sodium polystyrene sulfonate (Kayexalate) was the first synthetic polymeric sequestrant used for hyperkalemia. [16] Polyallylamine cross-linked polymers, such as Sevelamer (trade name Renagel), have also found therapeutic applications by oral administration as phosphate binders in hyperphosphatemia for kidney diseases. [17] Colesevelam hydrochloride (trade name WelChol) has been used as a bile acid binder for reducing cholesterol levels.…”