Hypericum genus cosmeceutical application – A decade comprehensive review on its multifunctional biological properties

Silva, Ana Rita; Taofiq, Oludemi; Ferreira, Isabel C.F.R.; Barros, Lillian

doi:10.1016/j.indcrop.2020.113053

Cited by 30 publications

(20 citation statements)

References 159 publications

(229 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Plants have been successfully employed worldwide in traditional medicine to treat inflammation processes within the body. Therefore, there is a constant pursuit for novel and more efficient naturally occurring molecules or their synthetic derivatives as anti-inflammatory agents (Nunes et al, 2020;Silva et al, 2021b). The extracts exhibiting the lowest IC (Table 2) were CH (86 μg mL − 1 ), HLR (76 μg mL − 1 ), and PHLR (73 μg mL − 1 ), followed by HLAP (243 μg mL − 1 ) and PHLAP (223 μg mL − 1 ).…”

Section: Anti-inflammatory Activitymentioning

confidence: 99%

“…Scientists have been collecting evidence that plant extracts enhance conventional antibiotic and preservative activities, serving as adjuvants and replacements. Accordingly, the search for novel compounds derived from plants has become an emergent area of great interest for the development of combined treatments (Cheesman et al, 2017;Silva et al, 2021b;Srivastava et al, 2014). The five hydroethanolic extracts obtained from C. hypocistis and H. lasianthum were assessed for their antibacterial activity (Table 3) against Gram+ and Gram-bacteria.…”

Section: Antimicrobial Activitymentioning

confidence: 99%

See 1 more Smart Citation

Evaluation of parasite and host phenolic composition and bioactivities − The Practical Case of Cytinus hypocistis (L.) L. and Halimium lasianthum (Lam.) Greuter

Silva

Ayuso

Pereira

et al. 2022

Industrial Crops and Products

Self Cite

View full text Add to dashboard Cite

show abstract

Section: Anti-inflammatory Activitymentioning

confidence: 99%

Section: Antimicrobial Activitymentioning

confidence: 99%

Evaluation of parasite and host phenolic composition and bioactivities − The Practical Case of Cytinus hypocistis (L.) L. and Halimium lasianthum (Lam.) Greuter

Silva

Ayuso

Pereira

et al. 2022

Industrial Crops and Products

Self Cite

View full text Add to dashboard Cite

show abstract

“…The scientific studies on multifunctional cosmetics have raised in recent years. 25 . In some other studies functional cosmetics have been developed by using herbal bio surfactants to stabilize, the vitamin C added to creams or the active ingredients in anti-dandruff shampoos 26 .…”

Section: Critical Factors and Steps In Designing Multifunctional Cosmetic Productsmentioning

confidence: 99%

Evaluation of Multifunctionality in Cosmetics

et al. 2021

View full text Add to dashboard Cite

In recent years, developments in the field of cosmetic ingredients especially use of natural sources and carriers systems and the manufacturing methods resulted as an improvement in the effect and stability of cosmetics, and thus the performance and component-based multi-functionalities of cosmetic products. Those have partially contributed to the condition-dependent functionality, developments in the field of marketing, monitoring of expectations and their reflection on marketing and the creation of new ideas in the field of claim-driven multi-functionality. Multi-functionality in cosmetic products can be evaluated in four groups. These are performance-based multi-functionality, component-based multi-functionality, conditional multi-functionality and claim-driven multi-functionality. In the first two groups, performance related to formulation and manufacturing comes to the fore, while in the last two, safety becomes important and those are briefly given in this review. Peer Review History: Received: 12 May 2021; Revised: 11 June; Accepted: 25 June, Available online: 15 July 2021 Academic Editor: Ahmad Najib, Universitas Muslim Indonesia, Makassar, Indonesia, ahmad.najib@umi.ac.id UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file: Reviewer's Comments: Average Peer review marks at initial stage: 6.0/10 Average Peer review marks at publication stage: 7.5/10 Reviewer(s) detail: Dr. Govind Vyas, Compliance & Regulatory Officer Inva-Tech Pharmaceuticals LLC, New-Jersey, USA, govindvyas03@gmail.com Dr. Mohammad Bayan, Faculty of Pharmacy, Philadelphia University, P.O. Box: 1 Philadelphia University 19392 Jordan, mbayan01@qub.ac Dr. Sally A. El-Zahaby, Pharos University in Alexandria, Egypt, sally.elzahaby@yahoo.com

show abstract

“…There are about 460 species of the genus Hypericum which distributed in temperate and subtropical regions worldwide (Liu et al, 2019). Up to now, numerous constituents including naphthodianthrones, phloroglucinol derivatives, flavonoids, and phenolic acids with documented biological activities have been isolated from Hypericum plants (Silva et al, 2021). Pharmacological studies have shown that these compounds have various biological activities such as antitumor, antibacterial, antioxidant, antiviral, antiangiogenic and anti‐inflammatory activities (Silva et al, 2021).…”

Section: Introductionmentioning

confidence: 99%

“…Up to now, numerous constituents including naphthodianthrones, phloroglucinol derivatives, flavonoids, and phenolic acids with documented biological activities have been isolated from Hypericum plants (Silva et al, 2021). Pharmacological studies have shown that these compounds have various biological activities such as antitumor, antibacterial, antioxidant, antiviral, antiangiogenic and anti‐inflammatory activities (Silva et al, 2021). Because of their structural complexity and potential pharmacological effects, this kind of compound has attracted extensive scientific interest.…”

Section: Introductionmentioning

confidence: 99%

Flavonoids from Hypericum patulum enhance glucose consumption and attenuate lipid accumulation in HepG2 cells

et al. 2021

View full text Add to dashboard Cite

Hypericum patulum has been used as a folk medicine for its varied therapeutic effects including antifungal, wound‐healing, spasmolytic, stimulant, hypotensive activities. The water decoction is drank as tea could treat cold, infantile malnutrition. The present study aims to isolate the constituents of the plant and investigate their effects on the glucose consumption in insulin‐resistant HepG2 cells, furthermore, lipid metabolism in oleic acid (OA)‐treated HepG2 cells was also studied. The phytochemical investigation of the plant led to the isolation of eleven compounds, and their structures were identified by spectroscopic analysis as n‐dotriacontanol (1), shikimic acid (2), 1‐O‐caffeoylquinic acid methyl ester (3), 5‐O‐caffeoylquinic acid methyl ester (4), 5‐O‐coumaroylquinic acid methyl ester (5), 5‐O‐caffeoylquinic acid butyl ester (6), quercetin‐3‐O‐α‐L‐rhamnoside (7), quercetin (8), quercetin‐3‐O‐(4״‐methoxy)‐α‐L‐rahmnopyranosyl (9), hyperoside (10), and rutin (11). The results revealed that compounds 7, 9, and 10 could enhance glucose consumption significantly in hyperglycemia induced HepG2 cells and insulin‐resistant HepG2 cells. In addition, the western blotting analysis result exhibited that compounds 7, 9, and 10 in high concentration (5 μM, H) group could dramatically upregulate the expression of PPARγ protein, and even the effect of them had no significant difference compared with that of rosiglitazone. Furthermore, compounds 9 and 10 in middle concentration (2.5 μM, M) group and H group could dramatically promote triglyceride metabolism and decrease TG content in OA‐treated HepG2 cells, and even in H group, reactive oxygen species (ROS) level were significantly decreased compared with model group. Practical applications Hypericum patulum is a well‐known plant of the genera Hypericum for its varied preventive and therapeutic potential activities. To study the chemical constituents and their effects on glucose and lipid metabolism in vitro, we detected glucose consumption in insulin‐resistant HepG2 cells, triglyceride content and reactive oxygen species level in OA‐treated HepG2 cells. In addition, PPARγ protein was also detected by western blotting analysis in the study. Compounds 1, 2, 3, 5, 6, 9, 10, and 11 were isolated from the plant for the first time. Quercetin‐3‐O‐(4"‐methoxy)‐α‐L‐rahmnopyranosyl (9) and hyperoside (10) had potential therapeutic benefit against glucose and lipid metabolic disease. Therefore, this study might have certain guiding significance for further research and development of H. patulum.

show abstract

Hypericum genus cosmeceutical application – A decade comprehensive review on its multifunctional biological properties

Cited by 30 publications

References 159 publications

Evaluation of parasite and host phenolic composition and bioactivities − The Practical Case of Cytinus hypocistis (L.) L. and Halimium lasianthum (Lam.) Greuter

Evaluation of parasite and host phenolic composition and bioactivities − The Practical Case of Cytinus hypocistis (L.) L. and Halimium lasianthum (Lam.) Greuter

Evaluation of Multifunctionality in Cosmetics

Flavonoids from Hypericum patulum enhance glucose consumption and attenuate lipid accumulation in HepG2 cells

Contact Info

Product

Resources

About