Hyperhomocysteinemia and Arterial Aneurysm

Cacoub, Patrice; Sbaï, A.; Brochériou, Isabelle; Kaloustian, E; Cohen, Gregory H.; Kieffer, Édouard; Pietté, J.C.

doi:10.1007/s10016-001-0026-7

Cited by 3 publications

(1 citation statement)

References 10 publications

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“…They also observed increased expression of matrix metalloproteinase-2 and -9 (MMP-2 and -9) in aneurysm of arterial walls. The study by Takagi et al [3] suggested that circulating MMP-9 concentrations were higher in patients with abdominal aortic aneurysm, and Cacoub et al [4] reported 2 male patients with the age of 32 and 38 of isolated aneurysm of both popliteal arteries and the right cubital artery in association with MTHFR mutation and hyperhomocysteinaemia, respectively. Mohan et al [5] reported a 64-year old man with hyperhomocysteinaemia in association with MTHFR mutation and an isolated left external iliac artery aneurysm.…”

Section: Discussionmentioning

confidence: 99%

Brachial artery aneurysm accompanying a homozygous methylenetetrahydrofolate reductase mutation

Güler

Tavlasoglu

Arslan

et al. 2013

Interactive CardioVascular and Thoracic Surgery

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Elevated plasma homocysteine (Hcy) is one of the suggested risk factors for endothelial dysfunction. There is evidence of association between raised plasma Hcy and an increased risk of developing peripheral arterial disease. A causal relationship, however, has not been established. In this report, a 37-year old male patient with the complaints of intermittent hand pain is presented. Brachial artery aneurysm accompanying a homozygous methylenetetrahydrofolate reductase mutation was detected.

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Section: Discussionmentioning

confidence: 99%