Hyperhidrosis of the residual limb: a narrative review of the measurement and treatment of excess perspiration affecting individuals with amputation

Lannan, Ford M.; Powell, Jordan; Kim, Gabriel M.; Hansen, Chuck; Pasquina, Paul F.; Smith, Douglas G.

doi:10.1097/pxr.0000000000000040

Cited by 13 publications

(10 citation statements)

References 83 publications

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“…Focal hyperhidrosis can also frequently occur after limb amputation, where the remaining residual limb excessively perspires, leading to an increased risk of dermatological disorders and functional limitations, such as the inability to wear a prosthesis comfortably or safely. Although many treatments have been proposed to treat residual hyperhidrosis within the dermatology community, they are not widely known by healthcare providers typically involved in caring for individuals with acquired limb loss [ 23 ].…”

Section: Resultsmentioning

confidence: 99%

Efficacy and Safety of Botulinum Toxin B in Focal Hyperhidrosis: A Narrative Review

Campanati

Diotallevi

Radi

et al. 2023

Toxins

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Botulinum toxin type B (BoNT-B), known as Myobloc® in the United States and as Neurobloc® in Europe, is a new therapeutically available serotype among the botulinum toxin family. During the last years several data have been reported in literature investigating its efficacy and safety, as well as defining the dosing and application regiments of BoNT-B in the treatment of hyperhidrosis. Moreover, recent studies have been examining its safety profile, which may be different from those known about BoNT-A. The aim of this review is to provide information about what is currently known about BoNT-B in regards to the treatment of focal hyperhidrosis.

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Section: Resultsmentioning

confidence: 99%

Efficacy and Safety of Botulinum Toxin B in Focal Hyperhidrosis: A Narrative Review

Campanati

Diotallevi

Radi

et al. 2023

Toxins

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show abstract

“…TEWL often uses a handheld device to measure the skin's water vapor output whereas SEC measures the change of capacitance at the skin surface, a correlate to the hydration of the skin. Excess sweat can predispose the skin to maceration and breakdown 33 . The residual limb has decreased barrier function, as measured by TEWL and SEC, relative to individuals without amputation 31 .…”

Section: Discussionmentioning

confidence: 99%

“…Excess sweat can predispose the skin to maceration and breakdown. 33 The residual limb has decreased barrier function, as measured by TEWL and SEC, relative to individuals without amputation. 31 This difference is especially pronounced in transtibial residual limbs compared to transfemoral.…”

Section: Barrier Functionmentioning

confidence: 99%

The relationship between residual limb health, motion within the socket, and prosthetic suspension

Baumann

Price

Brousseau

et al. 2022

PM&R

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Residual limb health is critical for continued prosthesis use; however, many prosthesis users experience skin‐related breakdown. The interface between the residual limb and the prosthetic socket sets the local mechanical environment and plays a role in skin stresses. Motion of the residual limb in the socket adds additional mechanical strain on the limb. This article explores the relationship between motion of the limb in the socket and residual limb health. We evaluated current methods for assessing residual limb health and motion of the residual limb in the socket and compared these evaluations across different prosthetic suspension systems. While few direct studies comparing residual limb health and motion exist, it has been shown that elevated vacuum suspension systems result in both improved residual limb health compared to passive suction and pin‐lock systems and decreased motion compared to passive suction, pin‐lock, knee sleeve, and anatomical suspension systems. While motion and health have not been directly linked, elevated vacuum suspension may demonstrate a relationship that reduced motion of the residual limb in the socket improves residual limb health. Further evaluation in this area is necessary to more completely and directly understand the relationship between residual limb motion and residual limb health.

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“…Especially, excessive perspiration causes clothing to stick to the skin and generate chills, which is detrimental to thermal comfort. 214,215 Therefore, it is imperative to design fabrics that promote comfort and productivity while facilitating effective evaporation of perspiration and heat dissipation.…”

Section: Responsive Thermoregulatory Textilesmentioning

confidence: 99%

“…Creating functional textiles with a cooling effect is essential for human thermal comfort during daily activities. ,, Although passive fabrics provide an efficient cooling effect, they have several thermal limitations in real-world situations. Especially, excessive perspiration causes clothing to stick to the skin and generate chills, which is detrimental to thermal comfort. , Therefore, it is imperative to design fabrics that promote comfort and productivity while facilitating effective evaporation of perspiration and heat dissipation.…”

Section: Responsive Thermoregulatory Textilesmentioning

confidence: 99%

Recent Advances in Thermoregulatory Clothing: Materials, Mechanisms, and Perspectives

et al. 2023

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Personal thermal management (PTM) is a promising approach for maintaining the thermal comfort zone of the human body while minimizing the energy consumption of indoor buildings. Recent studies have reported the development of numerous advanced textiles that enable PTM systems to regulate body temperature and are comfortable to wear. Herein, recent advancements in thermoregulatory clothing for PTM are discussed. These advances in thermoregulatory clothing have focused on enhancing the control of heat dissipation between the skin and the localized environment. We primarily summarize research on advanced clothing that controls the heat dissipation pathways of the human body, such as radiation-and conductance-controlled clothing. Furthermore, adaptive clothing such as dual-mode textiles, which can regulate the microclimate of the human body, as well as responsive textiles that address both thermal performance (warming and/or cooling) and wearability are discussed. Finally, we include a discussion on significant challenges and perspectives in this field, including large-scale production, smart textiles, bioinspired clothing, and AI-assisted clothing. This comprehensive review aims to further the development of sustainably manufactured advanced clothing with superior thermal performance and outstanding wearability for PTM in practical applications.

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Hyperhidrosis of the residual limb: a narrative review of the measurement and treatment of excess perspiration affecting individuals with amputation

Cited by 13 publications

References 83 publications

Efficacy and Safety of Botulinum Toxin B in Focal Hyperhidrosis: A Narrative Review

Efficacy and Safety of Botulinum Toxin B in Focal Hyperhidrosis: A Narrative Review

The relationship between residual limb health, motion within the socket, and prosthetic suspension

Recent Advances in Thermoregulatory Clothing: Materials, Mechanisms, and Perspectives

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