Hyperelastic modelling of arterial layers with distributed collagen fibre orientations

Gasser, Thomas C.; Ogden, Ray W.; Holzapfel, Gerhard

doi:10.1098/rsif.2005.0073

Cited by 1,895 publications

(1,840 citation statements)

References 83 publications

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“…The RAE is composed of a network of scaffold fibers and a network of collagen fibers. For both networks the initial fiber distributions are described by the fiber volume fractions φ γ i and φ γ i (i = c, s referring to collagen and scaffold respectively) along each direction γ with the periodic version of the normal distribution function introduced by Gasser et al (2006) and adapted by Driessen et al (2008): Fig. 1 Normal fiber volume fraction described in Eq.…”

Section: Microscale Growth and Degradation Modelmentioning

confidence: 99%

Modeling the impact of scaffold architecture and mechanical loading on collagen turnover in engineered cardiovascular tissues

Argento

Jonge

Söntjens

et al. 2014

Biomech Model Mechanobiol

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Section: Microscale Growth and Degradation Modelmentioning

confidence: 99%

Modeling the impact of scaffold architecture and mechanical loading on collagen turnover in engineered cardiovascular tissues

Argento

Jonge

Söntjens

et al. 2014

Biomech Model Mechanobiol

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“…where the third term on the right-hand side is based on the Holzapfel-Gasser-Ogden form (Gasser et al 2006), with only one fiber family here, with…”

Section: Head Modelmentioning

confidence: 99%

“…The tissue, consisting of axons, is modeled with a continuum approach. In line with the head model used at the macroscopic level, an anisotropic Holzapfel-Gasser-Ogden model (Gasser et al 2006) is used with the same properties as the head model. Note that volume associated to these critical locations is statistically small, so that the average tissue properties at the microstructural level correspond with those at the macroscopic level.…”

Section: Critical Volume Elementmentioning

confidence: 99%

Multi-scale mechanics of traumatic brain injury: predicting axonal strains from head loads

Cloots

Dommelen

Kleiven

et al. 2012

Biomech Model Mechanobiol

112

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The length scales involved in the development of diffuse axonal injury typically range from the head level (i.e., mechanical loading) to the cellular level. The parts of the brain that are vulnerable to this type of injury are mainly the brainstem and the corpus callosum, which are regions with highly anisotropically oriented axons. Within these parts, discrete axonal injuries occur mainly where the axons have to deviate from their main course due to the presence of an inclusion. The aim of this study is to predict axonal strains as a result of a mechanical load at the macroscopic head level. For this, a multi-scale finite element approach is adopted, in which a macro-level head model and a micro-level critical volume element are coupled. The results show that the axonal strains cannot be trivially correlated to the tissue strain without taking into account the axonal orientations, which indicates that the heterogeneities at the cellular level play an important role in brain injury and reliable predictions thereof. In addition to the multi-scale approach, it is shown that a novel anisotropic equivalent strain measure can be used to assess these micro-scale effects from head-level simulations only.

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“…The Gasser-Ogden-Holzapfel (GOH) model is a popular structurally based strain energy potential that is commonly used to model the behavior of arteries [14,15]. The GOH model has been chosen here to model the behavior of skin.…”

Section: Finite Element Analysismentioning

confidence: 99%

A combined experimental and numerical study of stab-penetration forces

Annaidh

Cassidy²,

Curtis³

et al. 2013

Forensic Science International

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Publication information Forensic Science International, 233 (1-3): 7-13Publisher Elsevier Item record/more information http://hdl.handle.net/10197/5939 Publisher's statementThis is the author's version of a work that was accepted for publication in Forensic Science International. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Forensic Science International (233, 1-3, (2013) AbstractThe magnitude of force used in a stabbing incident can be difficult to quantify, although the estimate given by forensic pathologists is often seen as 'critical' evidence in medico-legal situations.The main objective of this study is to develop a quantitative measure of the force associated with a knife stabbing biological tissue, using a combined experimental and numerical technique. A series of stab-penetration tests were performed to quantify the force required for a blade to penetrate skin at various speeds and using different 'sharp' instruments. A computational model of blade penetration was developed using ABAQUS/EXPLICIT, a non-linear finite element analysis (FEA) commercial package. This model, which incorporated element deletion along with a suitable failure criterion, is capable of systematically quantifying the effect of the many variables affecting a stab event. This quantitative data could, in time, lead to the development of a predictive model that could help indicate the level of force used in a particular stabbing incident.

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Hyperelastic modelling of arterial layers with distributed collagen fibre orientations

Cited by 1,895 publications

References 83 publications

Modeling the impact of scaffold architecture and mechanical loading on collagen turnover in engineered cardiovascular tissues

Modeling the impact of scaffold architecture and mechanical loading on collagen turnover in engineered cardiovascular tissues

Multi-scale mechanics of traumatic brain injury: predicting axonal strains from head loads

A combined experimental and numerical study of stab-penetration forces

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