Hyperdynamic Left Ventricular Ejection Fraction Have a Significantly Higher Need of Renal Replacement Therapy Probably Due to More Severe Vasoplegia: Any Other Potential Explanations?

The authors reply

“…We thank Honore et al (1) for describing other potential hemodynamic factors that could contribute to the increased prevalence of renal dysfunction in septic patients with hyperdynamic left ventricular ejection fraction (HDLVEF). In summary, we agree that there could be many contributing factors to the kidney injury observed in patients with HDLVEF.…”

“…RV dysfunction may also be associated with renal venous congestion (mentioned above). However, although there was a statistically significant difference in RVDil when comparing all three cohorts, this difference was not significant when comparing normal and HDLVEF cohorts alone (10.4% [63/604] vs 12.0% [18/150]; p = 0.309) (1). Again, the depressed LVEF cohort had seemingly greater disturbance in RV function, but no increase in RRT prevalence.…”