Hyperbaric oxygenation in peripheral ischaemic lesions in infants.

Rosenthal, Eric S.; Benderly, A; Monies-Chass, I.; Fishman, J.H.; Levy, José Guillermo de la Mora; Bialik, Viktor

doi:10.1136/adc.60.4.372

Cited by 14 publications

(5 citation statements)

References 6 publications

(1 reference statement)

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“…Epoprostenol infusion [45], sodium nitroprusside infusion in association with urokinase [10], topically applied nitroglycerine [21], hyperbaric oxygenation [42], and continuous caudal block [47] have been advocated to relieve peripheral ischaemia; however, only anecdotal reports have been published.…”

Section: Discussionmentioning

confidence: 99%

Are there specific haemostatic abnormalities in children surviving septic shock with purpura and having skin necrosis or limb ischaemia that need skin grafts or limb amputations?

Cremer

Leclerc

Jude³

et al. 1999

European Journal of Pediatrics

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In this series, the only difference between the two groups was lower factor VII levels in children with skin necrosis or limb ischaemia. This suggests the benefit of tissue factor pathway inhibitor administration as an adjunctive therapy to prevent skin necrosis or limb ischaemia. Further studies including more children are needed to determine the potential effects of treatments such as protein C, antithrombin, and plasminogen activator inhibitor antibody administration, and to advocate tissue factor pathway inhibitor in preventing skin necrosis or limb ischaemia.

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Section: Discussionmentioning

confidence: 99%

Are there specific haemostatic abnormalities in children surviving septic shock with purpura and having skin necrosis or limb ischaemia that need skin grafts or limb amputations?

Cremer

Leclerc

Jude³

et al. 1999

European Journal of Pediatrics

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“…66 -70 Several researchers have reported success in reducing mortality and the amount of amputated limb tissue by HBO adjunctive to the intensive care treatment. [71][72][73] HBO therapy should be instituted as soon as possible to reduce the extent of necrosis. The rationale for HBO is similar to that described for the treatment of acute peripheral ischemia.…”

Section: Purpura Fulminansmentioning

confidence: 99%

Hyperbaric Oxygen Therapy in the Pediatric Patient: The Experience of the Israel Naval Medical Institute

Waisman¹,

Shupak²,

Weisz

et al. 1998

Pediatrics

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We had a favorable experience with 129 of a total 139 pediatric patients treated at our facility for the indications listed. A basic knowledge of HBO therapy is needed to refer the pediatric patient for treatment when indicated. The needs of the pediatric patient, especially the critically ill, require specific skills and equipment inside the hyperbaric chamber. Close collaboration between the pediatrician and the hyperbaric medicine physician is essential to ensure adequate care for infants and children.

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“…Hyperbaric oxygen may be of benefit in P. fulminans during the phase of acute arterial ischemia, during resolution of ischemia perfusion injury, and during the healing phase. The use of hyperbaric oxygen for pediatric P. fulminans has been reported in seven case reports with a total of 23 patients (19)(20)(21)(22)(23)(24)(25). In these case reports, limb salvage was possible in 21 of the 23 patients.…”

Section: Discussionmentioning

confidence: 89%

Pediatric hyperbaric oxygen therapy in Victoria, 1998–2010

Frawley

Fock²

2012

Pediatric Critical Care Medicine

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Provision of hyperbaric oxygen to children with significant illness is feasible and associated with a low risk of complications. The most difficult aspect of managing pediatric hyperbaric oxygen therapy is in the coordination of the treatment with ongoing surgical and intensive care management. The lack of pediatric staff and facilities in major hyperbaric units necessitates multiple transfers for appropriate treatment.

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Hyperbaric oxygenation in peripheral ischaemic lesions in infants.

Cited by 14 publications

References 6 publications

Are there specific haemostatic abnormalities in children surviving septic shock with purpura and having skin necrosis or limb ischaemia that need skin grafts or limb amputations?

Are there specific haemostatic abnormalities in children surviving septic shock with purpura and having skin necrosis or limb ischaemia that need skin grafts or limb amputations?

Hyperbaric Oxygen Therapy in the Pediatric Patient: The Experience of the Israel Naval Medical Institute

Pediatric hyperbaric oxygen therapy in Victoria, 1998–2010

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