Hyperbaric Oxygen Therapy

Ingle, Robert B.

doi:10.1001/jama.1990.03450140031024

Cited by 5 publications

(4 citation statements)

References 5 publications

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“…The efficacy of hyperbaric oxygen therapy has been recorded in a lot of literature in clinical research community [71] [59] [16] [62]. The limited space of the hyperbaric oxygen chamber has constrained the possibilities of activities.…”

Section: Immersive Vr Glassessmentioning

confidence: 99%

Bigdata Oriented Multimedia Mobile Health Applications

Lv¹,

Chirivella²,

Gagliardo³

2016

J Med Syst

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In this paper, two mHealth applications are introduced, which can be employed as the terminals of bigdata based health service to collect information for electronic medical records (EMRs). The first one is a hybrid system for improving the user experience in the hyperbaric oxygen chamber by 3D stereoscopic virtual reality glasses and immersive perception. Several HMDs have been tested and compared. The second application is a voice interactive serious game as a likely solution for providing assistive rehabilitation tool for therapists. The recorder of the voice of patients could be analysed to evaluate the long-time rehabilitation results and further to predict the rehabilitation process.

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Section: Immersive Vr Glassessmentioning

confidence: 99%

Bigdata Oriented Multimedia Mobile Health Applications

Lv¹,

Chirivella²,

Gagliardo³

2016

J Med Syst

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show abstract

“…Hyperbaric oxygen therapy (HBOT) has been suggested for several conditions including age-associated diseases for more than 40 years ( Ingle, 1990 ; Leach et al, 1998 ), and it has recently been promoted as an approach to slow aging. HBOT is a method of treatment in which patients breathe in oxygen through a head tent, mask or endotracheal tube inside a hyperbaric chamber.…”

Section: Introductionmentioning

confidence: 99%

Effects of Hyperoxia on Aging Biomarkers: A Systematic Review

et al. 2022

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The effects of short-term hyperoxia on age-related diseases and aging biomarkers have been reported in animal and human experiments using different protocols; however, the findings of the studies remain conflicting. In this systematic review, we summarized the existing reports in the effects of short-term hyperoxia on age-related diseases, hypoxia-inducible factor 1α (HIF-1α), and other oxygen-sensitive transcription factors relevant to aging, telomere length, cellular senescence, and its side effects. This review was done as described in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline. A systematic search was done in PubMed, Google Scholar, and Cochrane Library and from the references of selected articles to identify relevant studies until May 2021. Of the total 1,699 identified studies, 17 were included in this review. Most of the studies have shown significant effects of short-term hyperoxia on age-related diseases and aging biomarkers. The findings of the studies suggest the potential benefits of short-term hyperoxia in several clinical applications such as for patients undergoing stressful operations, restoration of cognitive function, and the treatment of severe traumatic brain injury. Short-term hyperoxia has significant effects in upregulation or downregulation of transcription factors relevant to aging such as HIF-1α, nuclear factor kappa-light-chain-enhancer of activated B-cells (NF-kB), and nuclear factor (erythroid-derived 2)-like 2 (NRF2) among others. Short-term hyperoxia also has significant effects to increase antioxidant enzymes, and increase telomere length and clearance of senescent cells. Some of the studies have also reported adverse consequences including mitochondrial DNA damage and nuclear cataract formation depending on the dose and duration of oxygen exposure. In conclusion, short-term hyperoxia could be a feasible treatment option to treat age-related disease and to slow aging because of its ability to increase antioxidant enzymes, significantly increase telomere length and clearance of senescent cells, and improve cognitive function, among others. The reported side effects of hyperoxia vary depending on the dose and duration of exposure. Therefore, it seems that additional studies for better understanding the beneficial effects of short-term hyperoxia and for minimizing side effects are necessary for optimal clinical application.

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“…The oxygenation technology applied for ischemic heart therapy is based on the idea that blood oxygen partial pressure increase provides elimination of tissue hypoxia [18,19]. Starting from the 1940s, patients were efficiently treated with normobaric oxygenation; a bit later hyperbaric oxygenation (HBOT) technology was introduced [20][21][22]. The technology of hyperbaric medicine is effective for the treatment of ischemic brain damage [23,24], carbon monoxide poisoning [25], and a number of other clinical conditions [26,27].…”

Section: Introductionmentioning

confidence: 99%

Influence of hyperbaric oxygenation treatment (HBOT) on clinical outcomes (recurrent myocardial infarction and survival rate) during five-year monitoring period after acute myocardial infarction

Доценко¹,

Salivonchyk²,

Welcome³

et al. 2014

Health

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Surgical treatments of acute myocardial infarction (MI) possess a high clinical effectiveness, but there are fixed limitations, related to the patient's state, which are limited by medical resources and organizational problems. The development of new medical technologies provides a better and effective non-surgical treatment of acute MI and increases long-term prognosis in this category of patients. The study aims to investigate the influence of hyperbaric oxygenation treatment on clinical outcomes (survival rate and recurrent myocardial infarction (rMI)) during the five-year period of monitoring. The study involved 697 patients who suffered from acute MI, having undergone the standard treatment. The patients were randomly divided into two groups: Group 1 (reference, n = 363); Group 2 (test, n = 334). Patients of Group 2 were given the traditional treatment, accompanied with HBOT (isopression for forty minutes at a working pressure of 0.03 MPa). HBOT was applied first through the fifth day following MI. The treatment course included six cycles, once per day. The clinical assessment was focused on clinical outcome: rMI and mortality related to cardiovascular events. HBOT application that accompanied the acute MI with traditional pharmacotherapy has been proved to reduce rMI within five years following inpatient discharge (rMI rate was 14% in the reference group and 5.4% in the test group, χ 2 = 13.3, р < 0.05). The combination of HBOT with traditional methods in treating acute MI makes it possible to raise the five-year survival rate from 84.4% up to 95.9%.

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Hyperbaric Oxygen Therapy

Cited by 5 publications

References 5 publications

Bigdata Oriented Multimedia Mobile Health Applications

Bigdata Oriented Multimedia Mobile Health Applications

Effects of Hyperoxia on Aging Biomarkers: A Systematic Review

Influence of hyperbaric oxygenation treatment (HBOT) on clinical outcomes (recurrent myocardial infarction and survival rate) during five-year monitoring period after acute myocardial infarction

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