Hyperbaric oxygen therapy for Crohn’s disease complications: What do we know?

Hyperbaric oxygen therapy: More hope than hype for future treatment of perianal fistulizing Crohn's disease?

“…3 Perianal Crohn's disease is the most difficult phenotype to treat and it is associated with a poor quality of life and with poorer response to medical and surgical therapies. [4][5][6] Current treatment options are limited and the best medical and surgical therapies result in only about a third of patients remaining in remission at 1 year on maintenance treatment and sustained healing is often not achieved. 7 The authors mentioned that the greatest limitation of this study is the absence of a control group to really assess the effect of the additive treatment with hyperbaric oxygen therapy.…”

Hyperbaric oxygen therapy for Crohn’s disease complications: What do we know? –Authors’ reply

“…We want to thank Parra et al for their interest in our article “Wound healing of metastatic perineal Crohn’s disease using hyperbaric oxygen therapy: A case series”, and for sharing their experience with the treatment of patients with therapy‐refractory Crohn’s disease (CD) complications 1,2 …”

“…We want to thank Parra et al for their interest in our article "Wound healing of metastatic perineal Crohn's disease using hyperbaric oxygen therapy: A case series", and for sharing their experience with the treatment of patients with therapy-refractory Crohn's disease (CD) complications. 1,2 In their letter, the authors explain that the use of adjunctive hyperbaric oxygen (HBO) therapy is not a novel therapeutic strategy and that it has been used in therapeutic algorithms for more than a decade. Indeed, the use of HBO in inflammatory bowel disease (IBD) has been reported as early as 1989, and an emerging amount of scientific evidence is available.…”