Hyperbaric oxygen for the management of radionecrosis of bone and cartilage

London, Scott D.; Park, Stephen S.; Gampper, Thomas J.; Hoard, Martin A.

doi:10.1097/00005537-199809000-00005

Cited by 45 publications

(28 citation statements)

References 14 publications

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“…At present, the literature regarding use of hyperbaric oxygen for this condition is limited. 15 Use of hyperbaric oxygen to treat osteoradionecrosis of the mandible has been well documented, and such treatment has been shown to improve radiation-induced changes (i.e. hypoxia, hypocellularity and hypovascularity), creating an environment conducive to tissue healing and inhibitory to infection.…”

Section: Discussionmentioning

confidence: 99%

Surgical treatment of osteoradionecrosis of the temporal bone in patients with nasopharyngeal carcinoma

et al. 2008

J. Laryngol. Otol.

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Objective: To investigate methods of treating diffuse osteoradionecrosis of the temporal bone in cases of nasopharyngeal carcinoma, following radiotherapy.Study design: Retrospective. Methods: Fourteen post-irradiation nasopharyngeal carcinoma patients (n ¼ 14 ears) with diffuse osteoradionecrosis received surgical treatment from March 1994 to May 2005. The patients underwent radical mastoidectomy ( five ears), extensive radical mastoidectomy (one ear), or radical mastoidectomy and obliteration with local vascularised fascia flaps (eight ears).Results: Six ears fully recovered; two ears were still infectious but sequestrum had not re-formed; five ears (50 per cent) still had repeated suppuration and did not epithelialise; and one ear had local re-formation of sequestrum requiring periodic dressing changes.Conclusion: Diffuse osteoradionecrosis of the temporal bone following radiotherapy for nasopharyngeal carcinoma is difficult to treat surgically. The main objective of surgery is to facilitate drainage and to prevent complications. Radical mastoidectomy and obliteration with local vascularised flaps is an effective method.

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Section: Discussionmentioning

confidence: 99%

Surgical treatment of osteoradionecrosis of the temporal bone in patients with nasopharyngeal carcinoma

et al. 2008

J. Laryngol. Otol.

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“…Common complications reported are middle ear barotrauma 17,83 and myopia 42 . More severe but less common complications include pneumothorax, arterial air embolism, oxygen toxicity seizure, pulmonary oxygen toxicity or acute pulmonary edema 33,47,49,83 . HBO is contraindicated in patients with chronic obstructive pulmonary disease, poorly controlled chronic heart failure or with active tumour 17 , so it is not an option in many patients.…”

Section: Authormentioning

confidence: 99%

Incidence and prevention of osteoradionecrosis after dental extraction in irradiated patients: a systematic review

Nabil

Samman

2011

International Journal of Oral and Maxillofacial Surgery

282

266

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“…Its muscle tissue is considered particularly resistant to infection and plate exerted pressure [17]. When a free tissue transfer is not feasible, a viable treatment option supported by many authors is the use of the PMMC flap wrapped around an AO reconstruction plate for mandibular reconstruction to precisely bridge the mandibular defects [7,[17][18][19][20]. Ease of its application allows a relatively rapid and simple reconstructive option, especially in advanced or palliative cases or where the general condition of the patient does not allow for an extensive microvascular free flap transfer procedure [21].…”

Section: Discussionmentioning

confidence: 99%

Diagnostic Features and Management Strategy of a Refractory Case of Osteoradionecrosis of the Mandible: Case Report and Review of Literature

Jeyaraj¹,

Bandyopadhyay

2015

J. Maxillofac. Oral Surg.

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Introduction Osteoradionecrosis of the jaws produces a considerable amount of esthetic as well as functional deficits seriously affecting quality of life of the patient. Cases are often notoriously difficult to treat and manage owing to associated comorbidities of the patient, post irradiation fibrosis and decreased vascularity at the site, which complicates free tissue flap and graft transfer, that subsequently succumb to failure. Hyperbaric oxygen therapy (HBOT), in which 100 % oxygen is administered by mask under 2.4 atm pressure, in a hyperbaric oxygen chamber, helps by increasing local vascularity. Aim and Methods It was the aim of this study to show that a particularly refractory, compromised and challenging case of osteoradionecrosis can be managed successfully even without HBOT, by mandibular segmental resection followed by reconstruction using a titanium reconstruction plate enveloped within a pedicled Pectoralis Major Myocutaneous flap. Result Post operative recovery of the patient was excellent with good functional and esthetic rehabilitation of the patient with and practically nil donor site morbidity. Conclusion It is important to have a thorough knowledge of the clinical, radiographic, histopathologic, CT and MRI features of osteoradionecrosis of the jaws in order to make a quick and accurate confirmatory diagnosis and to overcome possible diagnostic dilemmas. The strategy of reconstruction of a large mandibular defect using a bridging titanium plate sandwiched by a healthy vascularized myocutaneous flap, following ablative surgery for ORN, has proved to be a safe and reliable option for composite mandibular defects, with gratifying long term functional and cosmetic results.

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Hyperbaric oxygen for the management of radionecrosis of bone and cartilage

Abstract: The successful use of hyperbaric oxygen for the management of radionecrosis of the head and neck is supported. The unusual prevalence of chondroradionecrosis may be an early reflection of changes in treatment protocols for patients with head and neck cancer.

Cited by 45 publications

References 14 publications

Surgical treatment of osteoradionecrosis of the temporal bone in patients with nasopharyngeal carcinoma

Surgical treatment of osteoradionecrosis of the temporal bone in patients with nasopharyngeal carcinoma

Incidence and prevention of osteoradionecrosis after dental extraction in irradiated patients: a systematic review

Diagnostic Features and Management Strategy of a Refractory Case of Osteoradionecrosis of the Mandible: Case Report and Review of Literature

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