The Cochrane Database of Systematic Reviews 2004
DOI: 10.1002/14651858.cd004617
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Hyperbaric oxygen as an adjuvant treatment for malignant otitis externa

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Cited by 21 publications
(33 citation statements)
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“…Regarding hyperbaric oxygen, there is as yet no uniformity in treatment design. Several reports suggested a beneficial effect of hyperbaric oxygen, along with traditional treatment 10 11 , whereas the Cochrane Collaboration Database 19 found no clear data supporting its efficacy relative to antibiotics and/or surgery.…”
Section: Discussionmentioning
confidence: 99%
“…Regarding hyperbaric oxygen, there is as yet no uniformity in treatment design. Several reports suggested a beneficial effect of hyperbaric oxygen, along with traditional treatment 10 11 , whereas the Cochrane Collaboration Database 19 found no clear data supporting its efficacy relative to antibiotics and/or surgery.…”
Section: Discussionmentioning
confidence: 99%
“…HBO requires daily treatments for several weeks and side effects include oxygen toxicity, barotrauma, and tympanic membrane perforation. A thorough review of the Cochrane Database, Medline, and Embase found no randomized controlled trials of HBO in MOE and concluded that no clear evidence exists to show the efficacy of HBO compared with antibiotic or surgical treatment [54].…”
Section: Managementmentioning
confidence: 99%
“…The main choice is ciprofloxacin due to bone penetration and oral availability [2] . Some advocate oxygen hyperbaric therapy as an adjuvant therapy, although its efficacy has not yet been thoroughly demonstrated [5] .…”
Section: Discussionmentioning
confidence: 99%