Hyperactive/impulsive symptoms and autistic trait in institutionalized children with maltreatment experience

Imai, Junko; Sasayama, Daimei; Kuge, Rie; Honda, Hideo; Washizuka, Shinsuke

doi:10.1002/cad.20445

Cited by 3 publications

(2 citation statements)

References 20 publications

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“…The clinical picture of maltreated children often shows features of ASD and ADHD. 29,30 These neurodevelopmentallike symptoms may result from epigenetic abnormalities originating from the DNA methylation of the FOXP1 gene.…”

Section: Discussionmentioning

confidence: 99%

Multi-Epigenome-Wide Analyses and Meta-Analysis of Child Maltreatment in Judicial Autopsies and Intervened Children and Adolescents

Tomoda,

Nishitani,

Fujisawa

et al. 2023

Preprint

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Child maltreatment (CM) leads to adverse outcomes in later life. We describe the epigenome-wide analyses and meta-analysis results of three original cohorts consisting of judicially or socially certified CM cases and controls to gain further insight into the epigenetic signatures engraved in maltreated children. We also show associations with biological indicators (endophenotypes) in each cohort that represent CM features with maltreatment history, thus providing further confidence in the identified methylations. Four methylations in ATE1, CHST11, SERPINB9P1, and FOXP1 associate with CM in the meta-analysis, in addition to several genome-wide level significant methylations in each cohort. FOXP1, a gene related to neurodevelopmental disorders, is of particular interest, as its methylation level correlates with atypical brain structures representing in maltreated children and contributes to the accuracy of a methylation risk score to predict CM. These results suggest that severe CM experiences may contribute to neurodevelopmental-like and traumatic symptoms via epigenetic alterations.

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Section: Discussionmentioning

confidence: 99%

Multi-Epigenome-Wide Analyses and Meta-Analysis of Child Maltreatment in Judicial Autopsies and Intervened Children and Adolescents

Tomoda,

Nishitani,

Fujisawa

et al. 2023

Preprint

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“…Larran et al ( 2021) present a systematic review to assess the feasibility of implementing three specific intervention methods designed for children with Autism Spectrum Disorder in schools welcoming refugee and asylumseeking children. Imai et al (2021) present a study examining how maltreatment experience is associated with autism spectrum disorder and attention deficit hyperactivity disorder symptoms in a large sample of children under institutional care in Japan. Braun and von Oertzen (2021) assessed the effect that mentors have on mentored children.…”

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confidence: 99%

Editorial—Directions 2021

Barbot¹

2021

New Drctns Chld & Adlscnt

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On behalf of the editorial team, I am pleased to introduce our first, yearly "Directions" issue. As presented in our inaugural editorial note (https://doi.org/10.1002/cad.20373; see also our "Manifesto", Barbot et al., 2020), New Directions for Child and Adolescent Development (NDCAD) offers this new, non-thematic issue format, that includes manuscripts falling within the aims and scope of the journal's mission. In other words, the Directions issue includes stand-alone papers that highlights important directions in the field of developmental science in general, or child and adolescent development in particular. Any type of submission not falling under a special issue or thematic issue will be considered under the Directions issue, but we seek preferably synthesis work (meta-reviews, metaanalyses), empirical work with unexpected findings or new interpretations and approaches to addressing longstanding issues, and new theoretical contributions. Contributions published in that issue may serve to initiate a dedicated NDCAD issue (whether Thematic Issue, or Special Issue).This kick-off issue provides a good sample of contributions that represent understudied topics, populations, and approaches. Larran et al. ( 2021) present a systematic review to assess the feasibility of implementing three specific intervention methods designed for children with Autism Spectrum Disorder in schools welcoming refugee and asylumseeking children. Imai et al. (2021) present a study examining how maltreatment experience is associated with autism spectrum disorder and attention deficit hyperactivity disorder symptoms in a large sample of children under institutional care in Japan. Braun and von Oertzen (2021) assessed the effect that mentors have on mentored children. They used a controlled design to investigate the causal effect of a mentor's presence on the mentee's empathic accuracy, cognitive functioning, and prosocial behaviors. Guignard et al. (2021) investigated the labeling effect of intellectually gifted adolescents in France on their school life satisfaction and peer connectedness. Their findings suggested that students labeled as gifted report lower level of peer connectedness, a factor that strongly contributes to school life satisfaction in this sample. Huang et al. (2021), examined the effects of group art therapy on self-concept and peer relationships among adolescents using a mixedmethod approach and found that such activity supports adolescents' self-concept and peer relationships. Martins et al. (2021) interviewed a large sample of Portuguese children from first to fourth grade and found a developmental trend in the concept of lying, which was associated with other moral reasoning dimensions: children could define lying accurately and considered it to be inappropriate, but many admitted to lie if a close adult requested it. Schipper and Koglin (2021) explored moral identity, moral emotion attribution, moral responsibility, acceptability, and moral decisions in a large sample of adolescents in Germany. Their findings showed...

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Maltreatment History and Internalizing and Externalizing Symptoms in Out-ofhome Care: A Three-Level Meta-analysis

Magalhães

Camilo

2023

The European Journal of Psychology Applied to Legal Context

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Hyperactive/impulsive symptoms and autistic trait in institutionalized children with maltreatment experience

Cited by 3 publications

References 20 publications

Multi-Epigenome-Wide Analyses and Meta-Analysis of Child Maltreatment in Judicial Autopsies and Intervened Children and Adolescents

Multi-Epigenome-Wide Analyses and Meta-Analysis of Child Maltreatment in Judicial Autopsies and Intervened Children and Adolescents

Editorial—Directions 2021

Maltreatment History and Internalizing and Externalizing Symptoms in Out-ofhome Care: A Three-Level Meta-analysis

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