Hyper reactive malarial splenomegaly (HMS).

Mk, Khan; Kamruzzaman, M; Quddus,

doi:10.3329/mmj.v15i2.45

Cited by 5 publications

(3 citation statements)

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“…This profile mirrors global data on the prevalence of fungal species in otomycosis. In this study, 90.3% of otomycosis cases were unilateral, consistent with the unilateral rates of 72-93% reported in previous studies [12,16] . The higher incidence rate of infection in the right ear compared to the left ear contradicts some studies results [14,17,18] but aligns with suspected moisture and anatomical factors [19] .…”

Section: Discussionsupporting

confidence: 92%

Exploring Antibiotic Susceptibility in Otomycosis: Uncovering Mixed Infections of Fungal and Bacterial Origin in Indonesia

Krisniawati,

Budhi Darmawan,

Puspita Karunia Ning Widhi

et al. 2023

IEM

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Backgrounds:Otomycosis is a common fungal ear infection affecting people worldwide. Cases may be exacerbated by mixed fungal-bacterial infections, especially those involving antibiotic-resistant bacteria. Understanding the microbiological features and antibiotic susceptibility patterns of the pathogens involved is critical for treatment. This study aimed to investigate the prevalence of mixed fungal-bacterial infections in otomycosis cases in Indonesia, to identify the bacterial species involved, and to determine their antibiotic susceptibility patterns. Materials & Methods: In this study, 47 ear swab specimens were collected from 41 clinically-diagnosed otomycosis cases from April to August 2022. The collected samples were processed by culture and microscopy to identify fungal and bacterial isolates. Antibiotic susceptibility testing was performed using the Kirby-Bauer disc diffusion method. Findings: Fungal isolates alone were detected in 80.9% of the specimens, while 19.1% showed mixed fungal-bacterial growth. The most common fungi were Aspergillus (57.1%) and Candida (42.9%) species. Among bacterial isolates, Staphylococcus aureus was the most frequent (observed in 66.7% of mixed cases), followed by Pseudomonas aeruginosa (22.2%). Also, two of the six S. aureus isolates were methicillin-resistant (MRSA). Both P. aeruginosa isolates were extended-spectrum beta-lactamase (ESBL) producers. Conclusion: Many otomycosis cases in this study demonstrated polymicrobial etiology. The emergence of antibiotic-resistant bacteria poses diagnostic and therapeutic challenges to healthcare systems.

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Section: Discussionsupporting

confidence: 92%

Exploring Antibiotic Susceptibility in Otomycosis: Uncovering Mixed Infections of Fungal and Bacterial Origin in Indonesia

Krisniawati,

Budhi Darmawan,

Puspita Karunia Ning Widhi

et al. 2023

IEM

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“…This explains the positive direct Comb's test found sometimes during malaria infection 8,9 . Splenomegaly in malaria contributes to anemia either by raised plasma volume, sequestration or as a result of hypersplenism resulting from tropical splenomegaly syndrome 10 . Until recently diagnosis of anemia in this area depends on clinical manifestation and anemia is treated by haematemics.…”

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confidence: 99%

Anemia in Kassala Area Eastern Sudan

Karoum¹,

Mohamed²,

Siddig³

et al. 2009

Sud Jnl Med Sci.

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ObjectiveThe objective of this study was to determine the types and the ways of diagnosis of anemia at Kassala region, Sudan. MethodsIn this study we examined and investigate 210 patients with anemia. Full blood cell count including peripheral picture, blood film for malaria, urine analysis and stool examination were done for every patient. Bone marrow aspiration was done for patients with splenomegaly with or without pancytopenia and or presence of immature cells in the peripheral blood. Serum iron and serum ferritin, for confirmation of iron deficiency were measured in some patients. ResultsOut of all patients, 45(21%) had chronic illness, 42(20%) had history of repeated attacks of malaria and 3(18%) patients had nutritional anemia. Sixty three (30%) patients presented with severe anemia, 32(15%) with mild anemia and 115(55%) with moderate anemia. Eighty patients presented with enlarge spleen. 26 (33%) out of the latter group had features of hypersplenism. ConclusionCommon causes of anemia in this area were chronic illness, followed by nutritional and repeated malaria infection. Splenomegaly and hypersplenism are common. We recommended that full blood count, peripheral blood picture and estimation of serum iron and serum ferritin should be performed for every anaemic patient. Blood film for malaria should be done for every anaemic patient and negative films should be repeated by immunochromatography test for plasmodium falciparum and vivax.

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“…This is particularly obvious in children while developing immunity to this common protozoan infection [21]. In some parts of Africa, the splenic enlargement rate is a marker of endemicity of malaria infection in children [22] while the tropical splenomegaly syndrome is a common finding in adults in such environment and in adults with hyper immune malarial syndrome [23] due to the development of an excessive immune reaction to the chronic presence of the malarial antigen in the circulation. Chronic granulocytic leukaemia is also another common cause of splenomegaly in Nigeria [24].…”

Section: Discussionmentioning

confidence: 99%

Unusually Located Keloids - The Role of Cultural Practices in its Etiology

Tat¹,

Irekpita²

2011

J Clin Exp Dermatol

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Keloids are an exuberant growth of scar tissue extending beyond the boundaries of the original wound causing it and are mainly due to excessive collagen tissue synthesis. They have predilection for certain sites in the human body.There is an increasing trend for the location of such keloidal scars in parts of the body where they are not supposed to be.Certain cultural practices are responsible for this situation particularly in the African context. One of such practice that leads to this type of unusual complication is presented below and the pathogenesis as well as other aspects of keloidal growth are reviewed in general. Figure 1: Below is also another perfectly healed scar done while the patient was young. Healing here is similar to the figure above. However, note the discolouration (? bluish hue) of the scars with its cosmetic effect! In some tribes, this is the reason for this practice. Unusually Located Keloids-The Role of Cultural Practices in its Etiology Journal of Clinical & Experimental Dermatology Research

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Hyper reactive malarial splenomegaly (HMS).

Cited by 5 publications

References 0 publications

Exploring Antibiotic Susceptibility in Otomycosis: Uncovering Mixed Infections of Fungal and Bacterial Origin in Indonesia

Exploring Antibiotic Susceptibility in Otomycosis: Uncovering Mixed Infections of Fungal and Bacterial Origin in Indonesia

Anemia in Kassala Area Eastern Sudan

Unusually Located Keloids - The Role of Cultural Practices in its Etiology

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