Hydroxyurea appears beneficial in patients with beta-thalassaemia major and intermedia

Abstract

AbstrakPasien dengan kelainan bawaan pada rantai -globin mungkin mengalami gejala penyakit yang lebih ringan jika mereka menghasilkan hemoglobin fetal (HbF) (2,5 -61,3%) menjadi 28,0% (6,6 -49,2%) dan 40,7% (4,8 -72,3%) Abstract Patients with severe inherited -globin chain disorders may have milder illness if they produce high levels of fetal hemoglobin (HbF). Hydroxyurea (HU) has been shown to enhance HbF levels in patients with sickle cell disease and may be useful in