Hydroxyapatite from fish scale for potential use as bone scaffold or regenerative material

Pon-On, Weeraphat; Suntornsaratoon, Panan; Charoenphandhu, Narattaphol; Thongbunchoo, Jirawan; Krishnamra, Nateetip; Tang, I‐Ming

doi:10.1016/j.msec.2016.01.051

Cited by 130 publications

(76 citation statements)

References 26 publications

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“…Further, the bone can be repeatedly boiled in distilled water to separate the organic tissue and bone marrow [4,6,11]. Degreasing and elimination of external hyaluronic acid and proteins can be achieved by bones immersion either in alcohol baths (ethanol 70%, v/v), followed by distilled water washing and hydrogen peroxide preservation (30%, v/v) or in alkaline sodium hydroxide (NaOH) solution (1 N) [4,12].…”

Section: Precursor's Preparation: Impurities and Organic Components Rmentioning

confidence: 99%

“…Dedicated studies offer extensive information regarding [1] marine resources such as vertebrates bones-fish bones [5,6,11,12] and calcified structures of invertebrates-coral, snail, seashell, cuttlefish, sea urchin, etc. [12][13][14][15][16][17], and [2] land resources such as animal bone tissue-preponderantly bovine bone [2,4,18,19] or other calcified structures such as eggshells [9,20], which could be used as cost-effective raw materials.…”

Section: Introductionmentioning

confidence: 99%

“…Initially proposed by Rathje in 1939 [25], the method was studied for different types of precursors in an attempt to obtain reproducible results [5,6,11,13,[16][17][18]26]. To date, the correlation between the synthesis parameters and the material characteristics is poorly understood, so further research is needed for adapting the method for advanced manufacturing.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Biomimetic Calcium Phosphates Derived from Marine and Land Bioresources

Miculescu¹,

Mocanu²,

Maidaniuc³

et al. 2018

Hydroxyapatite - Advances in Composite Nanomaterials, Biomedical Applications and Its Technological Facets

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This chapter aims to establish the key factors for technological optimization of biogenic calcium phosphate synthesis from marine and land resources. Three natural calcium sources-marble, seashell and bovine bone-were considered as raw materials. The proposed materials are suitable candidates for the synthesis of bone substitutes similar to the inorganic bone component. The synthesis processes were developed based on the investigations of thermal phenomena (TGA-DSC analysis) that can occur during thermal treatments. By this method, we were able to determine the optimum routes and temperatures for the complete dissociation of calcium carbonate as well as risk-free deproteinization of bovine bone. An exhaustive characterization, performed with modern and complementary techniques such as morphology (SEM), composition (EDS, XRF) and structure (FT-IR, XRD), is presented for each precursor. The final chemical composition of ceramic products can be modulated through a careful control of the key parameters involved in the conversion, in order to create long-term performant biphasic apatite biomaterials, with broad medical applicability. Identifying the suitable strategies for this modulation contributes to an appreciable advance in orthopedic tissue engineering.

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Section: Precursor's Preparation: Impurities and Organic Components Rmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Biomimetic Calcium Phosphates Derived from Marine and Land Bioresources

Miculescu¹,

Mocanu²,

Maidaniuc³

et al. 2018

Hydroxyapatite - Advances in Composite Nanomaterials, Biomedical Applications and Its Technological Facets

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“…In the 1980s, Hydroxyapatite (HA) was considered to be the material of choice for the development of bone substitutes to repair bone fractures and other defects due to its strong affinity with the mineral constituents of bones, good bioactivity, osteoconductivity, and biocompatibility with the human bone tissue . Although, stoichiometric HA, composed of calcium (Ca), phosphates (PO 4 ), and hydroxyl (OH) groups [Ca 10 (PO 4 ) 6 (OH) 2 ], the chemical composition of biological apatites differs from the stoichiometric HA .…”

Section: Introductionmentioning

confidence: 99%

Development of multisubstituted hydroxyapatite nanopowders as biomedical materials for bone tissue engineering applications

Ismail

Wimpenny

Bretcanu

et al. 2017

J Biomedical Materials Res

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Ionic substitutions have been proposed as a tool to control the functional behavior of synthetic hydroxyapatite (HA), particularly for Bone Tissue Engineering (BTE) applications. The effect of simultaneous substitution of different levels of carbonate (CO 3 ) and silicon (Si) ions in the HA lattice was investigated. Furthermore, human bone marrow-derived mesenchymal stem cells (hMSCs) were cultured on multi-substituted HA (SiCHA) to determine if biomimetic chemical compositions were osteoconductive. Of the four different compositions investigates, SiCHA-1 (0.58wt% Si) and SiCHA-2 (0.45wt% Si) showed missing bands for CO 3 and Si using FTIR analysis, indicating competition for occupation of the phosphate site in the HA lattice. 500°C was considered the most favourable calcination temperature as: (i) the powders produced possessed a similar amount of CO 3 (2-8wt%) and Si (<1.0wt%) as present in native bone; and (ii) there was a minimal loss of CO 3 and Si from the HA structure to the surroundings during calcination. Higher Si content in SiCHA-1 led to lower cell viability and at most hindered proliferation, but no toxicity effect occurred.While, lower Si content in SiCHA-2 showed the highest ALP/DNA ratio after 21 days culture with hMSCs, indicating that the powder may stimulate osteogenic behaviour to a greater extent than other powders.

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“…HAp derived from high temperature sintering of fish scales [80,81], fish bone [82,83], bovine bone [84] and pig bone [85] have also been used for development of composite bone scaffolds. Thus it is seen that bioceramic HAp has been derived from a wide range of natural sources like corals, algae and shells and biowaste maerials like eggshells, scales and bones.…”

Section: Hap From Bones and Scalesmentioning

confidence: 99%

Naturally derived biomaterials for development of composite bone scaffold: A review

Barua

Deoghare

Deb

et al. 2018

IOP Conf. Ser.: Mater. Sci. Eng.

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E-mail: imon18enator@gmail.comAbstract. Over the last few decades, there has been an increasing demand of tissue engineered bone scaffolds as a substitute material for diseased or damaged bone segments. A variety of synthetic and natural biomaterials have been explored by researchers for development of composite scaffold. Naturally derived biomaterials have the advantages of immunomodulating, anti-toxic and biomimetic properties with the cellular environment in vivo, when compared to synthetic biomaterials. In this paper, different protein and polysaccharide based biomaterials used for developing composite bone scaffolds are reviewed. The properties of composite scaffolds developed from these biomaterials are highlighted. The study also includes different natural materials and biowastes which are used for deriving bioceramics for producing composite bone scaffolds. The overall study gives a brief idea on the importance of protein and polysaccharide based biomaterials and bioceramics for composite bone scaffold development and scope for future work in the field of naturally derived biomaterials.

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Hydroxyapatite from fish scale for potential use as bone scaffold or regenerative material

Cited by 130 publications

References 26 publications

Biomimetic Calcium Phosphates Derived from Marine and Land Bioresources

Biomimetic Calcium Phosphates Derived from Marine and Land Bioresources

Development of multisubstituted hydroxyapatite nanopowders as biomedical materials for bone tissue engineering applications

Naturally derived biomaterials for development of composite bone scaffold: A review

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