Hydroxyapatite Dip Coated and Uncoated Titanium Poly-Axial Pedicle Screws: An In Vivo Bovine Model

Yıldırım, Ömer Selim; Aksakal, Bünyamin; Hanyaloglu, Salih C.; Erdoğan, Fazlı; Okur, Ali

doi:10.1097/01.brs.0000210221.00778.c7

Cited by 32 publications

(18 citation statements)

References 31 publications

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“…Several studies have proven HA to be an effective coating substance to increase bone-screw interfaces. 42,43 The size and shape of the deposited HA crystals in this study are similar to that in bone. Furthermore, nanoscale HA-coated implants may exceed micron-scale HA coatings in implant retention and histopathologic results.…”

supporting

confidence: 60%

Biomechanical evaluation and surface characterization of a nano-modified surface on PEEK implants: a study in the rabbit tibia

Johansson¹,

Jimbo²,

Kjellin³

et al. 2014

IJN

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Polyether ether ketone (PEEK) is today frequently used as a biomaterial in different medical operations due to its excellent mechanical and chemical properties. However, the untreated surface of PEEK is bioinert and hydrophobic, and it does not osseointegrate in its pure form. The aim of this study was to evaluate a unique nano-modified surface of PEEK with respect to osseointegration. Forty-eight threaded, non-cutting PEEK implants were inserted bilaterally in the tibia of 24 rabbits. Half of the implants (n=24) were coated with nanocrystalline hydroxyapatite (test) and the remaining implants (n=24) were left uncoated (control). Half of the animals (n=12) were euthanized after 3 weeks of healing and the remaining (n=12) after 12 weeks. The implant retention was measured with a removal torque apparatus. Surface analysis was performed with interferometry, scanning electron microscopy, and X-ray photon spectroscopy to relate the removal torque to the applied surface. The test implants revealed a significantly higher retention after 3 weeks ( P =0.05) and 12 weeks ( P =0.028) compared to controls. The result of the present study proves that the addition of nanocrystalline hydroxyapatite coating to PEEK surfaces significantly increases its removal torque and biocompatibility.

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supporting

confidence: 60%

Biomechanical evaluation and surface characterization of a nano-modified surface on PEEK implants: a study in the rabbit tibia

Johansson¹,

Jimbo²,

Kjellin³

et al. 2014

IJN

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“…The most successful among these was the use of plasma-sprayed HA screws [13,16,32,34,45,49]. Osteoblast adhesion and differentiation is enhanced when bioactive titanium implant is used in comparison to titanium alone [49]. The bone-implant interface was different from mineralizing bone matrix or osteoid.…”

Section: Current Practice For the Diagnosis At Our Spinal Unitmentioning

confidence: 99%

“…It is best to combine visualisation of screws with another diagnostic or therapeutic procedures, e.g., spinal probe or caudal epidural injections (Figs. 4,5,6] Measures to reduce screw loosening Improving screw-bone bonding was the target for many studies [13,16,31,32,34,39,42,45,48,49]. The most successful among these was the use of plasma-sprayed HA screws [13,16,32,34,45,49].…”

Section: Current Practice For the Diagnosis At Our Spinal Unitmentioning

confidence: 99%

Inter-observer reliability of detecting Dynesys pedicle screw using plain X-rays: a study on 50 post-operative patients

et al. 2009

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“…Calf and sheep are the most frequently used animal models in spine research (Wilke et al, 1997;Sandén et al, 2001;Yildirim et al, 2006;Kettler et al, 2007). However, outbreaks of bovine spongiform encephalopathy, avian influenza, severe acute respiratory syndromes (SARS), and influenza A (HIN1), along with the related risk of the personnel working with potentially contaminated tissues, have made the selection of animal models for spine research more difficult than ever (Wells et al, 1998).…”

Section: Introductionmentioning

confidence: 99%

Anatomical Characteristics of Deer and Sheep Lumbar Spines: Comparison to the Human Lumbar Spine

et al. 2015

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SUMMARY: Deer and sheep spines are often used as models of the human spine. A prerequisite for the use of animal models is information regarding the interspecies differences in the parameters of general interest. This would clarify the limitations of each animal model and substantiate the applicability of the obtained results to humans. Since sufficient data appear to be currently unavailable, we sought to investigate the feasibility of using deer and sheep as animal models for studies on the human spine. The objective of this study was a thorough comparison of the anatomical parameters of deer and sheep spines with those of the human spine. We employed threedimensional reconstructions of computed tomography images, generated using figure analysis software, which facilitated quantitative analysis of the linear and curvature parameters and the geometric index of the vertebral bodies. Our findings represent a comprehensive database of the anatomical characteristics of the deer and sheep lumbar spines and their comparisons with those of the human lumbar spine. This study provides insight into the similarities and differences in the vertebral geometries between the human spine and the deer and sheep spines. We found that the differences are minimal and that they do not greatly compromise the utility of deer and sheep lumbar spines as models of the human lumbar spine.

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Hydroxyapatite Dip Coated and Uncoated Titanium Poly-Axial Pedicle Screws: An In Vivo Bovine Model

Abstract: Hydroxyapatite coating of titanium pedicle screws by the dipping method improved fixation and vertebral bone-implant interface, suggesting a decreased risk of a screw-loosening problem.

Cited by 32 publications

References 31 publications

Biomechanical evaluation and surface characterization of a nano-modified surface on PEEK implants: a study in the rabbit tibia

Biomechanical evaluation and surface characterization of a nano-modified surface on PEEK implants: a study in the rabbit tibia

Inter-observer reliability of detecting Dynesys pedicle screw using plain X-rays: a study on 50 post-operative patients

Anatomical Characteristics of Deer and Sheep Lumbar Spines: Comparison to the Human Lumbar Spine

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