Hydroxyapatite-Coated Unicompartmental Knee Arthroplasty

Epinette, Jean-Alain; Young, David; Morris, Hayden

doi:10.1007/978-2-8178-0851-2_43

Cited by 11 publications

(11 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…do not form a mechanically stable link between the implant and bone tissue, ways have been sought to improve the mechanical contact at the interface [ 708 , 709 ]. The major way is to coat the metal with calcium orthophosphate ceramics that generally exhibit bone-bonding ability between the metal and bone [ 636 , 710 , 711 ]. The list of most important coating techniques is comprised in Table 5 , while the main advantages and drawbacks of each coating technique, as well as the important properties of the deposed calcium orthophosphates, are discussed in details elsewhere [ 268 , 288 , 289 , 712 , 713 , 714 , 715 , 716 , 717 , 718 , 719 , 720 ].…”

Section: Calcium Orthophosphates As Biomaterials and Bioceramicsmentioning

confidence: 99%

Calcium Orthophosphates in Nature, Biology and Medicine

Dorozhkin¹

2009

Materials

682

550

View full text Add to dashboard Cite

The present overview is intended to point the readers’ attention to the important subject of calcium orthophosphates. These materials are of the special significance because they represent the inorganic part of major normal (bones, teeth and dear antlers) and pathological (i.e. those appearing due to various diseases) calcified tissues of mammals. Due to a great chemical similarity with the biological calcified tissues, many calcium orthophosphates possess remarkable biocompatibility and bioactivity. Materials scientists use this property extensively to construct artificial bone grafts that are either entirely made of or only surface-coated with the biologically relevant calcium ortho-phosphates. For example, self-setting hydraulic cements made of calcium orthophosphates are helpful in bone repair, while titanium substitutes covered by a surface layer of calcium orthophosphates are used for hip joint endoprostheses and as tooth substitutes. Porous scaffolds made of calcium orthophosphates are very promising tools for tissue engineering applications. In addition, technical grade calcium orthophosphates are very popular mineral fertilizers. Thus ere calcium orthophosphates are of great significance for humankind and, in this paper, an overview on the current knowledge on this subject is provided.

show abstract

Section: Calcium Orthophosphates As Biomaterials and Bioceramicsmentioning

confidence: 99%

Calcium Orthophosphates in Nature, Biology and Medicine

Dorozhkin¹

2009

Materials

682

550

View full text Add to dashboard Cite

show abstract

“…As metals do not undergo bone bonding, i.e ., do not form a mechanically stable link between the implant and bone tissue, methods have been sought to improve contacts at the interface. The major way is to coat metals with calcium orthophosphate bioceramics that exhibit a bone-bonding ability between the metal and bone [ 60 , 179 , 190 , 315 , 475 , 476 , 477 , 478 , 479 , 480 ]. Thickness of the coatings vary from submicron dimensions to several hundreds microns ( Table 5 ) and this parameter appears to be very important.…”

Section: Biomedical Applicationsmentioning

confidence: 99%

Calcium Orthophosphates as Bioceramics: State of the Art

Dorozhkin¹

2010

JFB

214

112

View full text Add to dashboard Cite

In the late 1960s, much interest was raised in regard to biomedical applications of various ceramic materials. A little bit later, such materials were named bioceramics. This review is limited to bioceramics prepared from calcium orthophosphates only, which belong to the categories of bioactive and bioresorbable compounds. There have been a number of important advances in this field during the past 30–40 years. Namely, by structural and compositional control, it became possible to choose whether calcium orthophosphate bioceramics were biologically stable once incorporated within the skeletal structure or whether they were resorbed over time. At the turn of the millennium, a new concept of calcium orthophosphate bioceramics—which is able to promote regeneration of bones—was developed. Presently, calcium orthophosphate bioceramics are available in the form of particulates, blocks, cements, coatings, customized designs for specific applications and as injectable composites in a polymer carrier. Current biomedical applications include artificial replacements for hips, knees, teeth, tendons and ligaments, as well as repair for periodontal disease, maxillofacial reconstruction, augmentation and stabilization of the jawbone, spinal fusion and bone fillers after tumor surgery. Exploratory studies demonstrate potential applications of calcium orthophosphate bioceramics as scaffolds, drug delivery systems, as well as carriers of growth factors, bioactive peptides and/or various types of cells for tissue engineering purposes.

show abstract

“…A C C E P T E D M A N U S C R I P T ACCEPTED MANUSCRIPT 11 predetermined. In view of this, the growth mechanisms of thermally sprayed deposits are not established.…”

Section: Introductionmentioning

confidence: 99%