Hydroxyapatite-coated total hip replacement in Paget's disease: 20 patients followed for 4-8 years

Kirsh, George; Kligman, M; Roffman, M

doi:10.1080/000164701317323363

Cited by 19 publications

(18 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our results are in agreement with previously reported series [1,11,14,17,27] and close to those described in cementless hydroxyapatite fully coated THAs implanted in patients without PDB [3,7,8,34]. The control of PDB activity in the pre-operative period reduces the risk of implant loosening and the abnormal intra-operative blood loss.…”

Section: Discussionsupporting

confidence: 83%

“…In recent years, the use of uncemented components in PDB has been proposed and reported with promising results with regard to the mid-term outcome and fixation [1,11,14,17,27]. However, the benefits from the use of uncemented components remain unclear as active PDB may compromise the fixation and altered quality and morphological features of pagetic bone may influence bone ingrowth into cementless implants.…”

Section: Discussionmentioning

confidence: 99%

“…Recently, the use of cementless implants in patients with PDB has been reported with encouraging results [1,11,14,17,27].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Cementless total hip arthroplasty in Paget’s disease of bone: a retrospective review

Wegrzyn¹,

Pibarot²,

Chapurlat³

et al. 2009

International Orthopaedics (SICOT)

View full text Add to dashboard Cite

Paget's disease of bone (PDB) is a localised chronic osteopathy leading to bone deformities, bone hypervascularity, structural weakness and altered joint biomechanics. The pelvis and upper femur are frequently involved, resulting in disabling hip disease, and total hip arthroplasty (THA) may be required. We performed a retrospective study on the management and the outcome of 39 uncemented hydroxyapatite fully-coated THA in patients with PDB of the hip. The follow-up averaged 79.4 months (range 24-194). Functional scores improved significantly and, using the Harris hip score, 84% of patients had an excellent clinical outcome at the latest follow-up. Despite one case of an uncemented acetabular component with probable loosening, no implant revision had been required at our latest follow-up. Signs of implant loosening were found to be significantly more frequent in patients with active disease. For this reason, we advocate the use of pre-operative medication with bisphosphonates to reduce disease activity. Another benefit of this treatment is the significant decrease of intra-operative blood loss. Provided the control of disease activity in the pre-operative period with bisphosphonates is achieved, good outcome of cementless THAs can be expected. Bisphosphonates reduced the risk of implant loosening and excessive intra-operative blood loss

show abstract

Section: Discussionsupporting

confidence: 83%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Cementless total hip arthroplasty in Paget’s disease of bone: a retrospective review

Wegrzyn¹,

Pibarot²,

Chapurlat³

et al. 2009

International Orthopaedics (SICOT)

View full text Add to dashboard Cite

show abstract

“…Four cementless THA studies were included in this review as shown in ►Table 1, all of which were case series (level of evidence [LoE] IV) and had a mean MINORS score of 5.4. [13][14][15][16] There were a total of 97 patients with 111 THAs, with a mean age of 73.5 years at the time of operation and a mean followup of 8.2 years. PDB affected the femur alone in 15.3% of patients, the acetabulum alone in 58.6% of patients, and both the femur and acetabulum in 26.1% of patients.…”

Section: Cementless Total Hip Arthroplasty Study Characteristicsmentioning

confidence: 99%

“…[6][7][8][9][10][11][12] This has led to a recent trend in the literature with several studies using cementless THAs. [13][14][15][16] However, concerns also exist with cementless THA, as it is not known how the deranged morphology of the pagetoid bone affects the ingrowth of the cementless prosthesis. 2 Currently, there are no studies comparing the outcomes of cemented and cementless THA in the literature in PDB.…”

mentioning

confidence: 99%

Cemented versus Cementless Total Hip Arthroplasty in Paget's Disease of Bone: A Systematic Review

et al. 2017

View full text Add to dashboard Cite

The purpose of this study is to systematically review the clinical evidence for the use of cemented and cementless total hip arthroplasty (THA) in Paget's disease of bone (PDB), and to ascertain whether any difference exists in clinical outcomes between the two implant types. MEDLINE, EMBASE, and the Cochrane Library databases were searched in accordance with the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines. The quality of the studies was assessed using the methodological index for nonrandomized studies (MINORS) checklist. The reported clinical outcomes were evaluated using risk ratio (RR) with a p < 0.05 considered as statistically significant. Thirteen clinical studies with 444 primary THAs were included in this review. Cementless THA resulted in lower rates of aseptic loosening and lower rates of revision due to aseptic loosening (p < 0.05), but there was no overall statistically significant increase in the incidence of revision in the cemented THAs (p = 0.21). The postoperative Harris hip score was similar between both the groups. Also, the presence of heterotrophic ossification was similar in both the groups. Functional outcomes and survivorship were equivalent using either cementless or cemented components, with a similar rate of overall revisions. However, cementless components resulted in a decreased incidence of aseptic loosening and revision due to aseptic loosening. The current literature consists of a low level of evidence, level IV, which limits the conclusion of this study.

show abstract

Paget’s Disease

Kenanidis

Leonidou²,

Sakellariou

et al. 2018

The Adult Hip - Master Case Series and Techniques

View full text Add to dashboard Cite

Hydroxyapatite-coated total hip replacement in Paget's disease: 20 patients followed for 4-8 years

Cited by 19 publications

References 11 publications

Cementless total hip arthroplasty in Paget’s disease of bone: a retrospective review

Cementless total hip arthroplasty in Paget’s disease of bone: a retrospective review

Cemented versus Cementless Total Hip Arthroplasty in Paget's Disease of Bone: A Systematic Review

Paget’s Disease

Contact Info

Product

Resources

About