Hydroxyapatite-based nanoparticles as a coating material for the dentine surface: An antibacterial and toxicological effect

Erdem, Ümit; Doğan, Mustafa; Metin, Ayşegül Ülkü; Bağlar, Serdar; Turkoz, Mustafa; Türk, Mustafa; Nezir, S.

doi:10.1016/j.ceramint.2019.08.260

Cited by 41 publications

(34 citation statements)

References 48 publications

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“…The amplitude peak corresponding to the C element, found at around 0.3 eV, could be attributed to graphite conductive tape, too. None of the EDS spectra for any of the three samples mark the presence of trace elements, as reported in the literature [ 18 , 36 , 37 , 38 ].…”

Section: Resultsmentioning

confidence: 71%

“…Nowadays, one of the most promising approaches is hydroxyapatite synthesis from hen egg-shell sources due to the mimetic composition and structure of the carbonated apatite obtained compared with human bone [ 36 , 37 , 38 ]. Such carbonated apatite is prepared using several routes, including dry methods (solid state [ 39 ] and mechanochemical synthesis [ 40 ]), wet methods (precipitation [ 41 , 42 , 43 ], hydrolysis, sol–gel [ 44 ], emulsion [ 45 ], sonochemical [ 46 ], hydrothermal [ 47 , 48 ], and solvothermal [ 49 , 50 ]), or high-temperature methods (pyrolysis, combustion, and microwave heating [ 50 ]).…”

Section: Introductionmentioning

confidence: 99%

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Nano-Hydroxyapatite vs. Xenografts: Synthesis, Characterization, and In Vitro Behavior

et al. 2021

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This research focused on the synthesis of apatite, starting from a natural biogenic calcium source (egg-shells) and its chemical and morpho-structural characterization in comparison with two commercial xenografts used as a bone substitute in dentistry. The synthesis route for the hydroxyapatite powder was the microwave-assisted hydrothermal technique, starting from annealed egg-shells as the precursor for lime and di-base ammonium phosphate as the phosphate precursor. The powders were characterized by Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM), energy-dispersive X-ray analysis (EDAX), transmission electron microscopy (TEM), X-ray fluorescence spectroscopy (XRF), and cytotoxicity assay in contact with amniotic fluid stem cell (AFSC) cultures. Compositional and structural similarities or differences between the powder synthesized from egg-shells (HA1) and the two commercial xenograft powders—Bio-Oss®, totally deproteinized cortical bovine bone, and Gen-Os®, partially deproteinized porcine bone—were revealed. The HA1 specimen presented a single mineral phase as polycrystalline apatite with a high crystallinity (Xc 0.92), a crystallite size of 43.73 nm, preferential growth under the c axes (002) direction, where it mineralizes in bone, a nano-rod particle morphology, and average lengths up to 77.29 nm and diameters up to 21.74 nm. The surface of the HA1 nanoparticles and internal mesopores (mean size of 3.3 ± 1.6 nm), acquired from high-pressure hydrothermal maturation, along with the precursor’s nature, could be responsible for the improved biocompatibility, biomolecule adhesion, and osteoconductive abilities in bone substitute applications. The cytotoxicity assay showed a better AFSC cell viability for HA1 powder than the commercial xenografts did, similar oxidative stress to the control sample, and improved results compared with Gen-Os. The presented preliminary biocompatibility results are promising for bone tissue regeneration applications of HA1, and the study will continue with further tests on osteoblast differentiation and mineralization.

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Section: Resultsmentioning

confidence: 71%

Section: Introductionmentioning

confidence: 99%

Nano-Hydroxyapatite vs. Xenografts: Synthesis, Characterization, and In Vitro Behavior

et al. 2021

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“…2a shows the XRD patterns of HAP, Ag 3 PO 4 , AgBr, Ag 3 PO 4 /AgBr and 1:1-Ag 3 PO 4 / AgBr/HAP. Among them, the hydroxyapatite synthesized by oyster shells completely corresponds to the HAP standard spectrum (PDF#09-0432) card, 16,17 and the peak shape is sharp without impurity peaks, indicating that the HAP synthesized by this method is of high purity and good crystallinity. Similarly, the strong diffraction peaks of Ag 3 PO 4 at 2q ¼ 33.29 and 36.59 correspond to the (210) and (211) crystal planes of Ag 3 PO 4 (PDF#06-0505).…”

Section: Phase Structure and Morphologymentioning

confidence: 94%

Synthesis and visible-light photocatalytic degradation of Ag₃PO₄/AgBr/hydroxyapatite ternary nanocomposites prepared from oyster shells

et al. 2021

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“…Hydroxyapatite (HA), a non-toxic nano-material, is a promising inorganic material that immobilizes enzymes [ 14 , 15 ]. Adsorption of proteins on HA has been applied in a variety of applications such as in the chromatographic separation of proteins, bone regeneration in biomedical science, and drug delivery in the pharmaceutical industry [ 16 , 17 ].…”

Section: Introductionmentioning

confidence: 99%

Immobilization of Dextranase on Nano-Hydroxyapatite as a Recyclable Catalyst

Ding¹,

Zhang²,

Wang³

et al. 2020

Materials

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The immobilization technology provides a potential pathway for enzyme recycling. Here, we evaluated the potential of using dextranase immobilized onto hydroxyapatite nanoparticles as a promising inorganic material. The optimal immobilization temperature, reaction time, and pH were determined to be 25 °C, 120 min, and pH 5, respectively. Dextranase could be loaded at 359.7 U/g. The immobilized dextranase was characterized by field emission gun-scanning electron microscope (FEG-SEM), X-ray diffraction (XRD), and Fourier-transformed infrared spectroscopy (FT-IR). The hydrolysis capacity of the immobilized enzyme was maintained at 71% at the 30th time of use. According to the constant temperature acceleration experiment, it was estimated that the immobilized dextranase could be stored for 99 days at 20 °C, indicating that the immobilized enzyme had good storage properties. Sodium chloride and sodium acetic did not desorb the immobilized dextranase. In contrast, dextranase was desorbed by sodium fluoride and sodium citrate. The hydrolysates were 79% oligosaccharides. The immobilized dextranase could significantly and thoroughly remove the dental plaque biofilm. Thus, immobilized dextranase has broad potential application in diverse fields in the future.

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Hydroxyapatite-based nanoparticles as a coating material for the dentine surface: An antibacterial and toxicological effect

Cited by 41 publications

References 48 publications

Nano-Hydroxyapatite vs. Xenografts: Synthesis, Characterization, and In Vitro Behavior

Nano-Hydroxyapatite vs. Xenografts: Synthesis, Characterization, and In Vitro Behavior

Synthesis and visible-light photocatalytic degradation of Ag₃PO₄/AgBr/hydroxyapatite ternary nanocomposites prepared from oyster shells

Immobilization of Dextranase on Nano-Hydroxyapatite as a Recyclable Catalyst

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Hydroxyapatite-based nanoparticles as a coating material for the dentine surface: An antibacterial and toxicological effect

Cited by 41 publications

References 48 publications

Nano-Hydroxyapatite vs. Xenografts: Synthesis, Characterization, and In Vitro Behavior

Nano-Hydroxyapatite vs. Xenografts: Synthesis, Characterization, and In Vitro Behavior

Synthesis and visible-light photocatalytic degradation of Ag3PO4/AgBr/hydroxyapatite ternary nanocomposites prepared from oyster shells

Immobilization of Dextranase on Nano-Hydroxyapatite as a Recyclable Catalyst

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Synthesis and visible-light photocatalytic degradation of Ag₃PO₄/AgBr/hydroxyapatite ternary nanocomposites prepared from oyster shells