Hydroxyalkylation of Diethylvinylphosphonate in the Presence of DABCO

Baylis–Hillman Reaction as a Versatile Platform for the Synthesis of Diverse Functionalized Polymers by Chain and Step Polymerization

“…A novel method for the generation of functionalized polymers that has largely been under-explored is the use of monomers derived from the Baylis–Hillman reaction. The Baylis–Hillman reaction is a carbon–carbon bond forming reaction between an aldehyde and an activated alkene in presence of a tertiary amine such as DABCO (1,4-diazabicyclo[2.2.2]octane), and provides densely functionalized molecules in a one-pot process (Figure ). − Several activated alkenes such as acrylates, − acrylamides, acrylonitriles, vinyl ketones or vinyl phosphonates are substrates for the Baylis–Hillman reaction.…”

Baylis−Hillman-Type Carbon−Carbon Bond Formation of Alkenylphosphonates by the Action of Lithium Diisopropylamide

“…The conversion of 1 to 4 is equivalent to the Baylis−Hillman reaction. , We describe herein that treatment of a mixture of 1 and carbonyl compounds with LDA afforded 4 in good to high yields. Furthermore, we provide mechanistic evidence for the intermediacy of 2 .…”

Environmentally Benign Transformations of Monoterpenes and Monoterpenoids in Supercritical Fluids

“…The main products of the reaction at 413 K were keto alcohol 29 (44%) and diol 28 (30%); a-hydroxy aldehyde 30 was also identified with 2% yield (Scheme 6) [32]. The product distribution was similar to that obtained in the presence of montmorillonite clay [34] and differed sufficiently from that in the presence of ZnBr 2 [35].…”