Hydroxy(tosyloxy)iodobenzene (HTIB): A Convenient Oxidizing Agent for the Synthesis of Heterocycles

Abstract

Organo hypervalent iodine reagents are nowadays more attractive and versatile reagents for various chemical transformations in synthetic organic chemistry. These reagents are milder and having similar reactivity compared with toxic heavy metal reagents. Organo hypervalent iodine (λ3) reagents are successfully utilized to prepare synthetically and biologically important heterocycles. Hydroxy(tosyloxy)iodobenzene (HTIB) also acknowledged as Koser's reagent uses as an environmentally sustainable alternative to toxic heavy metals for the numerous and valuable organic transformations. The goal of this review is to highlight the recent advancements of the HTIB especially in the construction of heterocycles with various substitution patterns in a well‐organized form via tosyloxylation of ketones and oxidative cyclization methodology. This review compiles the up‐to‐date synthetic advancements of HTIB in the field of heterocycles.

Synergistic fabrication, characterization, and prospective optoelectronic applications of DES grafted activated charcoal dispersed PVA films

“…26,27 The dopant materials added to PVA alter its electronic properties, allowing for the creation of free charge carriers leading to electrical conductivity. 28,29 Modifying the dopant type and concentration can achieve various levels of conductivity, transforming insulating PVA into valuable semiconducting material for optoelectronic applications. [30][31][32] A novel and promising approach to achieving semiconducting properties in PVA involves the use of a dopant like Ternary Deep Eutectic Solvent (TDES) functionalized activated charcoal (TAC).…”

Modified eco‐friendly and biodegradable chitosan‐based sustainable semiconducting thin films

“…DES, derived from choline chloride, glycerine, and ethylene glycol, garners acclaim for its distinct features, comprising low toxicity, nature-friendly, and unique solvent properties, positioning it as a compelling candidate for various applications. In contrast, activated carbon with its microscale architecture, boasts excellent electrical, thermal, and mechanical characteristics, presenting prospects such as solar cells, photovoltaics, 12,13 photodetectors, and light-emitting devices. [14][15][16] Integration of DES-functionalized carbon into a polymer matrix enhances both structural and functional properties.…”

Introduction to hypervalent iodine chemistry. Part 3

“…37,43 Hypervalent iodine organosulfonates have found wide application as powerful electrophiles and oxidizing reagents. 23,31,61 The development of new synthetic methodologies and the use of hypervalent iodine reagents in specific classes of reactions have attracted significant research activity. In particular, radical and photochemical reactions of hypervalent iodine compounds have become one of the hottest areas of modern hypervalent iodine chemistry.…”