Pyrrolic-N-rich carbon
dots (CDs) that exhibit an absorption peak
in the first near-infrared (NIR) window region were developed using
a one-step microwave-assisted hydrothermal synthesis. A high concentration
of urea enabled the introduction of a large amount of pyrrolic-nitrogen
on the CD surfaces. Upon optimization of the experimental conditions,
the absorption peak of the CDs red-shifted from 550 to 650 nm. The
resulting pyrrolic-N-rich CDs exhibited photothermal effects with
high NIR photothermal efficiency (54.3%) and photoluminescence. The
prepared CDs, which show a first NIR window absorption peak, photoluminescence,
and negative surface charge, have the potential to be used as multifunctional
nanocarriers for cell imaging and drug delivery and as photothermal
agents in cancer therapy.