Hydrothermal calcium modification of 316L stainless steel and its apatite forming ability in simulated body fluid

Valanezahad, Alireza; Ishikawa, Kunio; Tsuru, Kanji; Maruta, Michito; Matsuya, Shigeki

doi:10.4012/dmj.2010-153

Cited by 4 publications

(3 citation statements)

References 21 publications

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“…3 and 4). The use of Ca 2+ to increase the rate of apatite formation has been previously reported 15,16) . Additionally, because CaCl2 solution is weakly alkaline 17) , it may increase both the Ca 2+ concentration and pH of the SBF (Fig.…”

Section: Discussionmentioning

confidence: 96%

Enhancement of apatite formation on Ti-50Zr alloy in simulated body environment

2023

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Ti-50Zr alloy is 2.5 times as strong as pure Ti and has a lower Young's modulus, making it a useful material for repairing bone and teeth. However, Ti-50Zr alloy has a limited ability to bond with bone in vivo. Under biological conditions, apatite formation at the surface of a Ti or alloy implant is necessary for its bonding with bone. Various approaches to surface modification have been proposed to impart bone-bonding ability to Ti-50Zr alloy; however, there remains a need for further improvements to the alloy's apatiteforming ability. Hence, in this study, we compared apatite formation at the surface of alloy substrates in simulated body fluid, after various surface treatments. Treatment with 5 M NaOH followed by 1 M CaCl2 was the most effective procedure, whereas a sample subjected to a hot water post-treatment formed less apatite. Notably, no apatite formed on samples treated with 10 M NaOH.

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Section: Discussionmentioning

confidence: 96%

Enhancement of apatite formation on Ti-50Zr alloy in simulated body environment

2023

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“…In order to enhance osteoconductivity of the scaffold, methods of surface modifications have been suggested in this study. Bioactive materials have been reported to bond to bone in vivo via formation of an apatite layer in the interface 17. Furthermore, the calcium ions (Ca 2+ ) in the apatite layer are thought to play a key role.…”

Section: Discussionmentioning

confidence: 99%

Bony defect repair in rabbit using hybrid rapid prototyping polylactic-co-glycolic acid/β-tricalciumphosphate collagen I/apatite scaffold and bone marrow mesenchymal stem cells

Pang

Jiang³

et al. 2013

IJOO

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Background:In bone tissue engineering, extracellular matrix exerts critical influence on cellular interaction with porous biomaterial and the apatite playing an important role in the bonding process of biomaterial to bone tissue. The aim of this study was to observe the therapeutic effects of hybrid rapid prototyping (RP) scaffolds comprising polylactic-co-glycolic acid (PLGA), β-tricalciumphosphate (β-TCP), collagen I and apatite (PLGA/β-TCP-collagen I/apatite) on segmental bone defects in conjunction with combination with bone marrow mesenchymal stem cells (BMSCs).Materials and Methods:BMSCs were seeded into the hybrid RP scaffolds to repair 15 mm defect in the radius of rabbits. Radiograph, microcomputed tomography and histology were used to evaluate new bone formation.Results:Radiographic analysis done from 12 to 36 weeks postoperative period demonstrated that new bone formed at the radial defect site and continues to increase until the medullary cavity is recanalized and remodelling is complete. The bone defect remained unconnected in the original RP scaffolds (PLGA/β-TCP) during the whole study. Histological observations conformed to the radiographic images. In hybrid RP scaffold group, woven bone united the radial defect at 12 weeks and consecutively remodeled into lamellar bone 24 weeks postoperation and finally matured into cortical bone with normal marrow cavity after another 12 weeks. No bone formation but connective tissue has been detected in RP scaffold at the same time.Conclusion:Collagen I/apatite sponge composite coating could improve new bone formation in vivo. The hybrid RP scaffold of PLGA/β-TCP skeleton with collagen I/apatite sponge composite coating is a promising candidate for bone tissue engineering.

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“…They reported that hydrothermal treatment in CaO solution enhanced the precipitation of apatite on the titanium surface [ 8 ]. Ishikawa et al proposed that Ti-O-Ca boding formed by hydrothermal treatment in CaCl 2 solution was effective for the fabrication of titanium implant with good bioactivity and osteoconductivity [ 9 , 10 ]. Hu et al referred to a one-step hydrothermal process with hydroxyapatite (HA) suspension to coat Ti surface [ 11 ].…”

Section: Introductionmentioning

confidence: 99%

Hydrothermal treatment of Ti surface to enhance the formation of low crystalline hydroxyl carbonate apatite

2015

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BackgroundTi and its alloys have been widely used as orthopedic and dental implants due to their outstanding mechanical properties and biocompatibility. However, long time is required to form bond between Ti implant and surrounding tissues. Therefore, these implants necessitate surface treatment such as mechanical/chemical treatment and coating of bioactive materials for improving the osseointegration.ResultsThis study was focused on the calcium-phosphate (Ca-P) coating on machined Ti, blasted-Ti (B-Ti), and blasted-NaOH-etched-Ti (BNH) surfaces by hydrothermal method to evaluate the ability of HA formation. Nanostructured morphology was created by NaOH etching on blasted-Ti surface. XRD analysis confirmed the existence of sodium titanate phase on such samples. Rutile and anatase phases along with hydroxyapatite were observed after hydrothermal treatment in Ca-P solution. Substantial hydroxyapatite together with TiO2 was observed during hydrothermal treatment at 200°C for 12 hrs. Blasted-NaOH-etched samples (BNH-Ti) revealed appreciable bone-like apatite formation as compared to machined-Ti and blasted-Ti (B-Ti) surfaces. However, maximum HA formation was confirmed on Ca-P coated-BNH samples (BNHA-Ti-200-12) by XRD and ICP analysis.ConclusionMultistep surface treatment adopted in current study would be effective to enhance HA formation on Ti surface.

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Hydrothermal calcium modification of 316L stainless steel and its apatite forming ability in simulated body fluid

Cited by 4 publications

References 21 publications

Enhancement of apatite formation on Ti-50Zr alloy in simulated body environment

Enhancement of apatite formation on Ti-50Zr alloy in simulated body environment

Bony defect repair in rabbit using hybrid rapid prototyping polylactic-co-glycolic acid/β-tricalciumphosphate collagen I/apatite scaffold and bone marrow mesenchymal stem cells

Hydrothermal treatment of Ti surface to enhance the formation of low crystalline hydroxyl carbonate apatite

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