Hydrophilisation of silicone rubber for medical applications

Abstract

Silicone rubber is one of the biomaterials used for preparation of medical implants. The properties of silicone rubber and methods of their evaluation are surveyed with respect to the medical applications. For some applications the hydrophobic character of silicone rubber is undesirable and possibilities of its hydrophilisation are presented in this review as well. Special attention is paid to the process of preparation of hydrophilic silicone rubber-hydrogel composite materials based on acrylic and methacrylic acids derivatives and to the properties of such materials.

Enhancing the protein resistance of silicone via surface-restructuring PEO–silane amphiphiles with variable PEO length

“…7-9 Various modifications have been utilized to hydrophilize silicones in order to reduce protein adsorption, including physical, chemical and combined approaches. 10-14 …”

Escherichia coliadhesion, biofilm development and antibiotic susceptibility on biomedical materials

“…Biomedical devices are currently made of different materials. SIL polymers have been further applied in urinary catheters, contact lenses, ophthalmologic implants, heart valves, breast implants, blood pumps, tubing and adhesives . Stainless steel (SS) 316 is used in surgical instruments and in orthopaedic, craniofacial, and cardiovascular implant devices .…”

Lipase Catalyzed Synthesis of Poly(ε-Caprolactone)−Poly(Dimethylsiloxane)−Poly(ε-Caprolactone) Triblock Copolymers

“…lead to materials for a wide range of potential applications [7,8]. Furthermore, silicone polymers have been applied in a wide range of medical devices, such as blood oxygenators, contact lenses, finger joints, catheters, blood pumps, breast implants, tubing, ophthalmologic implants, adhesives, tissue expanders and heart valves [9].…”