“… 36 However, there are numerous chemical derivatives of auristatin, i.e., MMAE, MMAF, MMAU, and AY, which differ in hydrophobicity, charge, and cytotoxicity. 20 , 22 , 39 , 69 Taking into account the plan to load FGF2 with three auristatin molecules, we decided to use more hydrophilic AY. Unlike MMAE, 39 AY did not show toxicity as a free drug ( Figure 7 , Table 2 ).…”