Hydrophilic Metal Nanoparticles Functionalized by 2-Diethylaminoethanethiol: A Close Look at the Metal–Ligand Interaction and Interface Chemical Structure

Venditti, Iole; Testa, Giovanna; Sciubba, Fabio; Carlini, Laura; Porcaro, Francesco; Meneghini, Carlo; Mobilio, Settimio; Battocchio, Chiara; Fratoddi, Ilaria

doi:10.1021/acs.jpcc.7b01424

Cited by 46 publications

(59 citation statements)

References 76 publications

(118 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Between 56 and 64% of the sulfur atoms were found to be bound to Ag atoms at the NP surface, with two distinct geometries in similar proportions. S 2p 3/2 components at binding energies (BE) of about 161 eV and 162 eV are attributed to sulfur atoms covalently bonded to metals in a monolayer or sub-monolayer regime, with the S atom in two different hybridizations, sp (161.3 eV) and sp 3 (162.1 eV), 16,17 coherently with what has already been observed for organic thiols chemisorbed onto gold surfaces. 18 The low BE signal is reported as occurring characteristically in selfassembling monolayers of low degree of coverage.…”

Section: Resultssupporting

confidence: 73%

“…The two hybridizations could mirror ligand binding on two different chemisorption sites, as hollow and on-top sites that favor stabilization of the assembly and dissolution into ions, respectively. 16,32 The current work therefore describes the proof of concept for the development of novel biocidal AgNP assemblies. An original nanomaterial with promising properties has been developed thanks to a tripodal tri-thiol molecule, whose thiolate functions interact with surface Ag(I) ions, thereby bridging the NPs.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Safer-by-design biocides made of tri-thiol bridged silver nanoparticle assemblies

et al. 2020

Self Cite

View full text Add to dashboard Cite

show abstract

Section: Resultssupporting

confidence: 73%

Section: Discussionmentioning

confidence: 99%

Safer-by-design biocides made of tri-thiol bridged silver nanoparticle assemblies

et al. 2020

Self Cite

View full text Add to dashboard Cite

show abstract

“…Correlation data have been acquired and fitted in analogy to our previous works [39,40]. All measurements were taken at least three times and the average value ± standard deviation was reported.…”

Section: Preparation Of Ufqdsmentioning

confidence: 99%

Sensitivity to Heavy-Metal Ions of Unfolded Fullerene Quantum Dots

Ciotta¹,

Paoloni²,

Prosposito³

et al. 2017

Preprint

Self Cite

View full text Add to dashboard Cite

A novel type of graphene-like quantum dots, synthesized by oxidation and cage-opening of C60 buckminsterfullerene, has been studied as a fluorescent and absorptive probe for heavy-metal ions.The lattice structure of such unfolded fullerene quantum dots (UFQDs) is distinct from that of graphene since it includes both carbon hexagons and pentagons. The basic optical properties, however, are similar to those of regular graphene oxide quantum dots. On the other hand, UFQDs behave quite differently in the presence of heavy-metal ions, in that multiple sensitivity to Cu 2+ , Pb 2+ and As(III) was observed through comparable quenching of the fluorescent emission and different variations of the transmittance spectrum. By dynamic light scattering measurements we confirmed, for the first time in metal sensing, that this response is due to multiple complexation and subsequent aggregation of UFQDs. Nonetheless, the explanation of the distinct behaviour of transmittance in the presence of As(III) and the formation of precipitate with Pb 2+ require further studies. These differences, however, also make it possible to discriminate between the three metal ions in view of the implementation of a selective multiple sensor.

show abstract

“…AuNPs can be synthesized by means of several processes such as chemical, physical, and biological methods [24,[49][50][51]65]. A well-known bottom-up approach is a wet reduction in the presence of a capping agent [55,57,[59][60][61][62]64]. The obtained AuNPs can be easily investigated by microscope techniques, such as transmission electron microscope (TEM), scanning electron microscope (SEM), and atomic force microscope (AFM) [98][99][100][101][102].…”

Section: Aunpsmentioning

confidence: 99%

“…In fact, they show remarkable chemical-physical properties, such as an easy modifiable morphology/size/surface, modulable optical absorption and scattering, photothermal and photoacoustic enhancements, and a wide surface/volume ratio that is suitable for interaction with the environment [50][51][52][53]. The gold surface can be functionalized and linked with drugs [54-57] and biomolecules, such as enzymes, antibodies, DNA, and peptides to achieve a specific site [58][59][60][61][62][63][64][65][66], and they are also studied to develop innovative antibacterial systems [67][68][69][70].In the wide field of advanced materials that represent the frontier where gold-based materials and nuclear medicine meet, this review provides an updated scenario of the progress in this young research field, focusing on gold nanoparticles (AuNPs) and nanorods (AuNRs) used in diagnosis and therapy, as schematized in Figure 1. The first key topic is the chemical preparation of gold-based nanomaterials, which is focused on spheres and rods.…”

mentioning

confidence: 99%

Gold Nanoparticles and Nanorods in Nuclear Medicine: A Mini Review

et al. 2019

Self Cite

View full text Add to dashboard Cite

In the last decade, many innovative nanodrugs have been developed, as well as many nanoradiocompounds that show amazing features in nuclear imaging and/or radiometabolic therapy. Their potential uses offer a wide range of possibilities. It can be possible to develop nondimensional systems of existing radiopharmaceuticals or build engineered systems that combine a nanoparticle with the radiopharmaceutical, a tracer, and a target molecule, and still develop selective nanodetection systems. This review focuses on recent advances regarding the use of gold nanoparticles and nanorods in nuclear medicine. The up-to-date advancements will be shown concerning preparations with special attention on the dimensions and functionalizations that are most used to attain an enhanced performance of gold engineered nanomaterials. Many ideas are offered regarding recent in vitro and in vivo studies. Finally, the recent clinical trials and applications are discussed.Radiopharmaceuticals are showing amazing outcomes in diagnostic (90%) and therapeutic (10%) applications for many diseases such as cancer, heart and brain diseases, and so on [33]. They consist of a radioactive nuclide linked to a biologically active molecule directed to the target of interest. When radionuclides emit γ rays (either directly, as pure γ emitters, or indirectly, as β+ emitters), the radiopharmaceutical is intended for diagnostic imaging. When radionuclides emit β− or α particles (thanks to the cell-damaging properties) the radiopharmaceutical is used for therapeutic applications and, in some recent research studies, even for radio-guided surgery [34][35][36]. Theragnostics is a new term that implies the use of the same molecule, labeled with different radionuclides, for both diagnostic and therapeutic purposes [37][38][39].Radiopharmaceuticals have been increasingly used for medical diagnosis since the late 1940s, when nuclear medicine was born. Nuclear medicine aims at evaluating both physiological function as well as biochemical changes in disease conditions; it includes two-dimensional (2D) imaging (planar scintigraphy) and three-dimensional (3D) imaging (single-photon emission computed tomography, SPECT, and positron emission tomography, PET). The functional information obtained by SPECT and PET may need to be coupled with the anatomic/morphologic information typically provided by computed tomography (CT) (hence SPECT and PET are now commonly called SPECT-CT and PET-CT): these approaches, named "hybrid imaging", have many advantages as well as high sensitivity, good spatial resolution, and the possibility to correctly locate functional abnormalities (by the SPECT or PET component) within a definite anatomic field (by the CT component) [34].The γ-emitting radionuclides that are used for planar and SPECT imaging are usually obtained within hospital nuclear medicine facilities (or research departments) from small portable generators; some are produced by nuclear reactors and then shipped to the hospital facility ready to use. The β+ emitting radionuclides ...

show abstract

Hydrophilic Metal Nanoparticles Functionalized by 2-Diethylaminoethanethiol: A Close Look at the Metal–Ligand Interaction and Interface Chemical Structure

Cited by 46 publications

References 76 publications

Safer-by-design biocides made of tri-thiol bridged silver nanoparticle assemblies

Safer-by-design biocides made of tri-thiol bridged silver nanoparticle assemblies

Sensitivity to Heavy-Metal Ions of Unfolded Fullerene Quantum Dots

Gold Nanoparticles and Nanorods in Nuclear Medicine: A Mini Review

Contact Info

Product

Resources

About