Hydrophilic Interaction Liquid Chromatography for the Analysis of
Pharmaceutical Formulations
Aleksandra Radoičić,
Sandra Šegan,
Aleksandra Dramićanin
et al.
Abstract:For a long time, Reversed-Phase Liquid Chromatography (RPLC) was the most dominant
technique for the analysis of pharmaceutical compounds, but with poor efficiency in the separation of
small polar molecules. From the efforts to solve the problem of insufficient retention of these molecules,
during the last decades, a mode of liquid chromatography named Hydrophilic Interaction Liquid
Chromatography (HILIC) has experienced vast expansion. It is based on the use of a highly hydrophilic
stationary phase along with… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.