Hydrophilic [60]fullerene carboxylic acid derivatives retaining the original 60π electronic system

Fluorescent fullerene nanoparticle-based lateral flow immunochromatographic assay for rapid quantitative detection of C-reactive protein

“…The absorption spectrum shows a strong peak at 272 nm and broad bands at 300–400 nm, indicating the results from carboxylation of C 60 -TEG which has weak broad band at 260 nm and 350 nm [14]. These features are similar to those of the spectra of the hydrophilic fullerene carboxylic acid derivative and fullerenol, respectively [23, 24]. In addition, the fluorescence spectrum of C 60 -TEG-COOH exhibits broad fluorescence with a maximum peak at 500 nm under excitation at 350 nm, which is slightly blue-shifted compared to the fluorescence ofC 60 -TEG, meaning that the carboxylation may lead to change of the optical properties from C 60 -TEG.…”

Tuning the Polarity of Fullerene C60 Derivatives for Enhanced Photodynamic Inactivation†

“…The reaction conditions, which previously proved fruitful for us (22,36,43), gave the expected fulleropyrrolidine 1 in 25% yield. Based on previous reports, the acid hydrolysis of the acetyl groups was next carried out using an excess of p-TsOH in toluene at 90°C (44), affording 98% of the diol derivative 2. Having a proficient pathway toward the fulleropyrrolidines 1 and 2, the next step was to introduce intrinsic positive charges in both molecular structures.…”

21 Fullerenes

“…125 Water soluble [60]fullerene carboxylic acid derivatives with the full 60 p-electron system have been prepared from a bis-fulleroid. 126 Fullerenols have been shown to have nitric oxide scavenging activity. 127 Fullerenols can also generate superoxide anions which result in membrane damage and cell death.…”