Hydrolysis of lignocellulose to succinic acid: a review of treatment methods and succinic acid applications

Zhou, Shuzhen; Zhang, Miaomiao; Zhu, Li-Yuan; Xiao-ling, Zhao; Chen, Junying; Chen, Wei; Chang, Chun

doi:10.1186/s13068-022-02244-5

Cited by 21 publications

(12 citation statements)

References 123 publications

(113 reference statements)

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“…The commercialized preparation of BDO and SA from renewable resources of hemicellulose and cellulose, respectively, has been established recently. − (Scheme ) In this work, a series of fully biobased copolyesters of PBC x BS y were synthesized with CBPC, SA, and BDO, where BC and BS represent the BDO–CBPC and BDO–SA units and x and y represent the molar percentages of CBPC and SA in the copolyesters, respectively. PBC x BS y was synthesized using a two-step melting procedure containing esterification and polycondensation.…”

Section: Resultsmentioning

confidence: 99%

Improving Thermal, Mechanical, and Crystalline Properties of Poly(butylene succinate) Copolyesters from a Renewable Rigid Diester

Yu,

Liu,

Wei

2023

ACS Sustainable Chem. Eng.

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The introduction of rigid cyclic monomers into the poly(butylene succinate) (PBS) backbone is the most common way to elevate its low glass-transition temperature (T g = −30.0 °C). However, the insertion of cyclic units always leads to very poor crystallinity and low molecular weight, which drastically hinder their industrial applications. Herein, a renewable rigid diester N,N′trans-1,4-cyclohexane-bis(pyrrolidone-4-methyl carboxylate) (CBPC) was obtained via Michael addition. CBPC with linked rings had high spatial mobility, resulting in high reaction reactivity. A series of biobased PBC x BS y copolyesters were prepared by melt polycondensation of CBPC with succinic acid and 1,4-butanediol, achieving the high-number-average molecular weight of up to 44.5 kDa. The insertion of CBPC led to higher thermal stability and dramatically enhanced the T g , such that the T g of PBC 80 BS 20 (87.5 °C) surpassed that of PBS (−30.0 °C) over 117.5 °C. Moreover, PBC x BS y showed an unexpected cocrystallization behavior, in which the rigid CBPC with a bulky tricyclic structure could be inserted into the crystal of PBS and formed a homogeneous crystalline structure. The cocrystallization was deeply analyzed by thermodynamic study and density functional theory calculation. Benefiting from the cocrystallization, PBC x BS y showed distinguished mechanical performances, which matched with or excelled those of the commercial polyesters of polyethylene terephthalate, polybutylene terephthalate, and polylactic acid. Accordingly, CBPC could be regarded as an effective biobased building block to spectacularly improve the thermal, mechanical, and crystalline performances of PBS at the same time.

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Section: Resultsmentioning

confidence: 99%

Improving Thermal, Mechanical, and Crystalline Properties of Poly(butylene succinate) Copolyesters from a Renewable Rigid Diester

Yu,

Liu,

Wei

2023

ACS Sustainable Chem. Eng.

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“…The first step of this process requires the degradation of lignocellulose into monosaccharides or aromatic compounds via enzymatic or chemical methods. This is followed by the use of different microbial metabolic pathways to produce lactic acid, 3-hydroxypropionic acid, succinic acid, fatty acids, DDA, and other products. − However, the formation of certain toxic intermediates during the pretreatment of lignocellulose affects the growth of microorganisms, reducing the conversion rate and increasing production costs. , Therefore, the development of efficient pretreatment processes to reduce the generation of toxic and harmful substances could alleviate the problem of resource depletion caused by the use of fossil fuel-derived materials such as alkanes for the production of long-chain DCAs. Further, it could also reduce the use of sugar-based carbon sources.…”

Section: Prospecting the Synthesis Of Dicarboxylic Acids From The Per...mentioning

confidence: 99%

Mid–Long Chain Dicarboxylic Acid Production via Systems Metabolic Engineering: Progress and Prospects

Gu,

Zhu,

Zhang

et al. 2024

J. Agric. Food Chem.

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Mid-to-long-chain dicarboxylic acids (DCA i , i ≥ 6) are organic compounds in which two carboxylic acid functional groups are present at the terminal position of the carbon chain. These acids find important applications as structural components and intermediates across various industrial sectors, including organic compound synthesis, food production, pharmaceutical development, and agricultural manufacturing. However, conventional petroleum-based DCA production methods cause environmental pollution, making sustainable development challenging. Hence, the demand for eco-friendly processes and renewable raw materials for DCA production is rising. Owing to advances in systems metabolic engineering, new tools from systems biology, synthetic biology, and evolutionary engineering can now be used for the sustainable production of energy-dense biofuels. Here, we explore systems metabolic engineering strategies for DCA synthesis in various chassis via the conversion of different raw materials into mid-to-long-chain DCAs. Subsequently, we discuss the future challenges in this field and propose synthetic biology approaches for the efficient production and successful commercialization of these acids.

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“…For instance, the hydrolysis of hemicelluloses produces xyloses, arabinoses, galactoses, and rhamnoses, but many host microorganisms in CBP cannot consume these sugars, leading to a carbon catabolite repression [192]. In such cases, CBP hosts are required to be modified by genetic engineering or metabolic engineering [32,193,194]. Another approach is the co-culture strategy by introducing other strains to metabolize these sugars and fully utilizing various carbohydrates in the lignocellulosic hydrolysates, thus improving the hydrolysis efficiency of upstream strains [191,195,196].…”

Section: Lignocellulose Hydrolysate In Different Biorefinery Strategiesmentioning

confidence: 99%

Composition of Lignocellulose Hydrolysate in Different Biorefinery Strategies: Nutrients and Inhibitors

Wang,

Zhang,

Cui

et al. 2024

Molecules

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The hydrolysis and biotransformation of lignocellulose, i.e., biorefinery, can provide human beings with biofuels, bio-based chemicals, and materials, and is an important technology to solve the fossil energy crisis and promote global sustainable development. Biorefinery involves steps such as pretreatment, saccharification, and fermentation, and researchers have developed a variety of biorefinery strategies to optimize the process and reduce process costs in recent years. Lignocellulosic hydrolysates are platforms that connect the saccharification process and downstream fermentation. The hydrolysate composition is closely related to biomass raw materials, the pretreatment process, and the choice of biorefining strategies, and provides not only nutrients but also possible inhibitors for downstream fermentation. In this review, we summarized the effects of each stage of lignocellulosic biorefinery on nutrients and possible inhibitors, analyzed the huge differences in nutrient retention and inhibitor generation among various biorefinery strategies, and emphasized that all steps in lignocellulose biorefinery need to be considered comprehensively to achieve maximum nutrient retention and optimal control of inhibitors at low cost, to provide a reference for the development of biomass energy and chemicals.

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Hydrolysis of lignocellulose to succinic acid: a review of treatment methods and succinic acid applications

Cited by 21 publications

References 123 publications

Improving Thermal, Mechanical, and Crystalline Properties of Poly(butylene succinate) Copolyesters from a Renewable Rigid Diester

Improving Thermal, Mechanical, and Crystalline Properties of Poly(butylene succinate) Copolyesters from a Renewable Rigid Diester

Mid–Long Chain Dicarboxylic Acid Production via Systems Metabolic Engineering: Progress and Prospects

Composition of Lignocellulose Hydrolysate in Different Biorefinery Strategies: Nutrients and Inhibitors

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