Hydrolysis of Chlorantraniliprole and Cyantraniliprole in Various pH Buffer Solutions

Abstract

The hydrolysis reactions of [(14)C]-chlorantraniliprole (CLAP) and cyantraniliprole (CNAP) were investigated in sterile buffer solutions at pH 4, 7, and 9. Both compounds displayed similar degradation reactions. The reactions observed were intramolecular cyclizations and rearrangements instead of the anticipated amide hydrolysis to carboxylic acids. Despite a minor difference in their structures, the degradation rates for the two compounds were substantially different. The reaction rates were examined at multiple temperatures to understand the mechanistic aspects of the underlying transformations. Similarities and differences in the hydrolysis behavior of these compounds in various pH values and temperatures are described.

Photometabolic pathways of chlorantraniliprole in aqueous slurries containing binary and ternary oxides of Zn and Ti

“…In addition, the DBE data and MS 2 experiments, conducted through the selection of the ions m/z 244 [M+HÀCl] + and 209 [M + HÀCl 2 ] + , are also consistent with the proposed structure MET 7. This transformation product was also identified by Sharma et al [42], although other intermediates detected by some authors in recent studies related to hydrolysis, and chemical and photochemical degradation of CL [37,42,43] were not recovered in our case. Fig.…”

Hydrolytic Activation Kinetics of the Herbicide Benzobicyclon in Simulated Aquatic Systems

“…The activation energies for each treatment were calculated as described by Sharma et al 31 The Arrhenius equation was applied to the results in the form of the equation:…”

“…The activation energies for each treatment were calculated as described by Sharma et al The Arrhenius equation was applied to the results in the form of the equation: where E A is the activation energy (kJ mol –1 ), R is the universal gas constant (0.008314 kJ mol –1 K –1 ), and A is the pre-exponential factor with the same units as k H (h –1 ). Plotting ln k H vs 1/ T gave a straight line with a slope equal to − E A / R with an intercept of ln A .…”

Effects of some Insecticides on some Biological Parameters of Cotton Leafworm, Spodoptera littoralis (Lepidoptera: Noctuidae)

“…Chlorantraniliprole is a new generation efficient anthranilic diamides insecticide developed by DuPont in 2000 (Sharma et al, 2014 andLahm et al, 2007), with many advantages such as high efficiency, low toxicity, broad spectrum, long persistence and low residue (Ren et al, 2008 andLahm et al, 2009). It has been reported to exhibit excellent efficacy against lepidopteran insects (Lavtizar et al, 2015).…”