Hydrolysis, Biodegradation and Ion Sorption in Binary Biocomposites of Chitosan with Polyesters: Polylactide and Poly(3-Hydroxybutyrate)

Роговина, С. З.; Zhorina, L. A.; Yakhina, Anastasia; Shapagin, A. V.; Iordanskii, A. L.; Берлин, А. А.

doi:10.3390/polym15030645

Cited by 4 publications

(4 citation statements)

References 41 publications

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“…With a rise in temperature, e.g., under heating of the chitosan samples, as provided by the DSC protocol, the partial and then full disrupture of the cross-linking formed by their hydrogen bonds transpires. On the thermograms, this process is accompanied by an endothermic gently sloping maximum that characterizes the intensity of H-bond destruction [ 23 , 34 , 35 ]. The second and third peaks correspond to different modes of PHB melting.…”

Section: Resultsmentioning

confidence: 99%

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Effect of Drug Encapsulation and Hydrothermal Exposure on the Structure and Molecular Dynamics of the Binary System Poly(3-hydroxybutyrate)-chitosan

et al. 2023

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In this work, film materials based on binary compositions of poly-(3-hydroxybutyrate) (PHB) and chitosan with different ratios of polymer components in the range from 0/100 to 100/0 wt. % were studied. Using a combination of thermal (DSC) and relaxation (EPR) measurements, the influence of the encapsulation temperature of the drug substance (DS) of dipyridamole (DPD) and moderately hot water (at 70 °C) on the characteristics of the PHB crystal structure and the diffusion rotational mobility of the stable TEMPO radical in the amorphous regions of the PHB/chitosan compositions is shown. The low-temperature extended maximum on the DSC endotherms made it possible to obtain additional information about the state of the chitosan hydrogen bond network. This allowed us to determine the enthalpies of thermal destruction of these bonds. In addition, it is shown that when PHB and chitosan are mixed, significant changes are observed in the degree of crystallinity of PHB, degree of destruction of hydrogen bonds in chitosan, segmental mobility, sorption capacity of the radical, and the activation energy of rotational diffusion in the amorphous regions of the PHB/chitosan composition. The characteristic point of polymer compositions was found to correspond to the ratio of the components of the mixture 50/50%, for which the inversion transition of PHB from dispersed material to dispersion medium is assumed. Encapsulation of DPD in the composition leads to higher crystallinity and to a decrease in the enthalpy of hydrogen bond breaking, and it also slows down segmental mobility. Exposure to an aqueous medium at 70 °C is also accompanied by sharp changes in the concentration of hydrogen bonds in chitosan, the degree of PHB crystallinity, and molecular dynamics. The conducted research made it possible for the first time to conduct a comprehensive analysis of the mechanism of action of a number of aggressive external factors (such as temperature, water, and the introduced additive in the form of a drug) on the structural and dynamic characteristics of the PHB/chitosan film material at the molecular level. These film materials have the potential to serve as a therapeutic system for controlled drug delivery.

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Section: Resultsmentioning

confidence: 99%

“…However, the high sensitivity of chitosan to moisture limits its application. This disadvantage can be overcome by mixing chitosan with moisture-resistant polymers such as PHB [ 21 , 22 , 23 ], polylactides [ 23 ], and polycaprolactone [ 24 ] provided that the biodegradability of the blends’ constituents must be saved.…”

Section: Introductionmentioning

confidence: 99%

Effect of Drug Encapsulation and Hydrothermal Exposure on the Structure and Molecular Dynamics of the Binary System Poly(3-hydroxybutyrate)-chitosan

et al. 2023

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“…In addition, the synergic effect of better-dispersed ChNCs with the assistance of OLA resulted in increased crystallinity, and, thereby, an improvement in the oxygen barrier performance modified films as compared to that of neat PLA. Rogovina and collaborators [ 7 ] analyzed the hydrolysis resistance, biodegradation-in-soil, and ion sorption behavior of film binary polyester–chitosan composites, such as polylactide (PLA)–chitosan and poly(3-hydroxybutyrate) (PHB)–chitosan. Chitosan combined with biodegradable polyesters (PLA and PHB) has been studied as a novel functional material capable of performing in aqueous environments and soil.…”

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“Polymers from Renewable Resources”: Key Findings from This Topic Special Issue

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“…The high water diffusivity of PLA [85] allows small molecules to permeate into the matrix. A recent study investigated the use of PLA-chitosan composites as metal absorbents for wastewater treatment [86]. The relatively low barrier properties of PLA pose a major challenge when using PLA as a food contact material.…”

Section: Migration and Sorption Propertiesmentioning

confidence: 99%

The Potential of Bio-Based Polylactic Acid (PLA) as an Alternative in Reusable Food Containers: A Review

O’Loughlin,

Doherty,

Herward

et al. 2023

Sustainability

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The biodegradable biopolymer polylactic acid (PLA) has been used in the recent past in single-use packaging as a suitable replacement for non-biodegradable fossil fuel-based plastics, such as polyethylene terephthalate (PET). Under FDA and EU regulations, lactic acid (LA), the building block of PLA, is considered safe to use as a food contact material. The mechanical, thermal, and barrier properties of PLA are, however, major challenges for this material. PLA is a brittle material with a Young’s modulus of 2996–3750 MPa and an elongation at break of 1.3–7%. PLA has a glass transition temperature (Tg) of 60 °C, exhibiting structural distortion at this temperature. The water permeability of PLA can lead to hydrolytic degradation of the material. These properties can be improved with biopolymer blending and composites. Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV), for instance, increases the thermal stability of PLA while decreasing the water permeability by up to 59%. Polypropylene (PP) is one of the most common plastics in reusable food containers. This study will compare PLA-based blends and composites to the currently used PP as a sustainable alternative to fossil fuel-based plastics. The end-of-life options for PLA-based food containers are considered, as is the commercial cost of replacing PP with PLA.

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Hydrolysis, Biodegradation and Ion Sorption in Binary Biocomposites of Chitosan with Polyesters: Polylactide and Poly(3-Hydroxybutyrate)

Cited by 4 publications

References 41 publications

Effect of Drug Encapsulation and Hydrothermal Exposure on the Structure and Molecular Dynamics of the Binary System Poly(3-hydroxybutyrate)-chitosan

Effect of Drug Encapsulation and Hydrothermal Exposure on the Structure and Molecular Dynamics of the Binary System Poly(3-hydroxybutyrate)-chitosan

“Polymers from Renewable Resources”: Key Findings from This Topic Special Issue

The Potential of Bio-Based Polylactic Acid (PLA) as an Alternative in Reusable Food Containers: A Review

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