Hydrogenation reactions catalyzed by HN(CH₂CH₂PR₂)₂-ligated copper complexes

Abstract

HN(CH2CH2PR2)2-ligated copper borohydride complexes, (RPNHP)Cu(BH4) (R = iPr, Cy, tBu), which can be prepared from (RPNHP)CuBr and NaBH4, are capable of catalyzing the hydrogenation of aldehydes in an alcoholic solvent....

Levulinic Acid Hydrogenation with Homogeneous Cu(I) Catalyst

“…[16] Recently, in 2021, Guan's group reported the use of [( R PN H P)CuBr] (2 mol %) as a catalytic precursor using a non-innocent ligand to promote H 2 activation. [17] All these systems require a large excess of a strong base (from 2 to 10 mol %) to allow the ketone hydrogenation. [18] We report the synthesis and characterization of a well-defined homogeneous Cu catalyst precursor and the first study of a homogeneous Cu-based catalyst in LVA selective hydrogenation to yield GVL with excellent selectivity (> 99 %) and high activity (TON = 4000), the current reaction conditions are rather competitive for the use of a first-row transition metal.…”

“…using the copper cluster [(PPh 3 )CuH] 6 (2–10 mol %), and Me 2 PPh (12–60 mol %) as a ligand [16] . Recently, in 2021, Guan's group reported the use of [( R PN H P)CuBr] (2 mol %) as a catalytic precursor using a non‐innocent ligand to promote H 2 activation [17] . All these systems require a large excess of a strong base (from 2 to 10 mol %) to allow the ketone hydrogenation [18] .…”