Hydrogenation of 4-Nitroacetophenone Over Rh/Silica: Understanding Selective Hydrogenation of Multifunctional Molecules

Multivariate Analysis in Selective Nitroacetophenone Conversion by Hydrogen Sulfide under Phase Transfer Catalysis

“…30−34 The reduction of p-NAP to the aniline−ketone, aniline−methylene, and aniline−alcohol by the hydrogenation reaction with different palladium, platinum, and rhodium catalysts have been studied by Hawkins et al 35 A few researchers have produced p-AAP from p-NAP by using homogeneous or heterogeneous catalysts such as bimetallic Rh 3 Ni 1 nanoparticles, ionic liquids, 36 and rhodium/silica catalyst. 37 There are some constraints related to those processes like the selectivity of products, waste minimization, environmental safety, and overall operational costs. The current reaction also follows the Zinin reduction pathway, but the approach of utilization of industrially available H 2 S-laden MDEA is a new one.…”

“…High-value chemical intermediates can be produced from aromatic amines, which are widely used as raw materials for many utility chemicals like fiber, explosives, polymers, cosmetics, pesticides, dyes, etc. − Anilines are industrially used as an intermediate for the production of dyes and artificial pigments. , Some patents are available on the reduction of p -NAP to corresponding amines or sometimes to alcohols by hydrogenation under high temperature and pressure in the presence of palladium or Raney nickel as catalysts. − The reduction of p -NAP to the aniline–ketone, aniline–methylene, and aniline–alcohol by the hydrogenation reaction with different palladium, platinum, and rhodium catalysts have been studied by Hawkins et al A few researchers have produced p -AAP from p -NAP by using homogeneous or heterogeneous catalysts such as bimetallic Rh 3 Ni 1 nanoparticles, ionic liquids, and rhodium/silica catalyst . There are some constraints related to those processes like the selectivity of products, waste minimization, environmental safety, and overall operational costs.…”