Hydrogen peroxide scavenging, antioxidant and anti-radical activity of some phenolic acids

Sroka, Zbigniew; Cisowski, Wojciech

doi:10.1016/s0278-6915(02)00329-0

Cited by 828 publications

(580 citation statements)

References 17 publications

Supporting

Mentioning

503

Contrasting

Unclassified

Order By: Relevance

“…As per the hypothesis already proposed, more the exothermic reactions of antioxidant with free radicals, lesser is the barrier which in turn leads the antioxidants to react faster with the radicals thereby preventing its reaction with the biological substrate [32] . We argue that 毩-TA is an effective antioxidant due to its larger BDE.…”

Section: Discussionmentioning

confidence: 76%

Evaluation of anti–apoptotic activity of different dietary antioxidants in renal cell carcinoma against hydrogen peroxide

Rai

Mangal

Sahu

et al. 2011

Asian Pacific Journal of Tropical Biomedicine

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 76%

Evaluation of anti–apoptotic activity of different dietary antioxidants in renal cell carcinoma against hydrogen peroxide

Rai

Mangal

Sahu

et al. 2011

Asian Pacific Journal of Tropical Biomedicine

View full text Add to dashboard Cite

“…Many recent studies have also confirmed strong antioxidant, antiradical and anticancer activities of some compounds of this group, e.g. caffeic acid, p-coumaric and protocatechuic acids (Laranjinha et al 1994;Nardini et al 1995;Rice-Evans et al 1996;Sroka and Cisowski 2003;Wen et al 2003;Ekiert and Czygan 2007;Sánchez-Maldonado et al 2011). Hydroxybenzoic acids also possess many others very important biological properties.…”

Section: Introductionmentioning

confidence: 87%

Accumulation of hydroxybenzoic acids and other biologically active phenolic acids in shoot and callus cultures of Aronia melanocarpa (Michx.) Elliott (black chokeberry)

Szopa

Muszyńska

2012

Plant Cell Tiss Organ Cult

View full text Add to dashboard Cite

Phenolic acids are plant metabolites important in phytotherapy and also in cosmetology. In this study, proliferating shoot and callus cultures of Aronia melanocarpa were established and maintained on Linsmaier and Skoog (L-S) medium containing different levels of a-naphthaleneacetic acid (NAA) and 6-benzyladenine (BA), ranging from 0.1 to 3.0 mg l -1 . Methanolic extracts from the biomass of these cultures and from the fruits of soil-grown plants were used to determine the amounts of free phenolic acids and cinnamic acid using the high-performance liquid chromatography (HPLC) method. Out of a total of twelve analyzed compounds, all of the extracts contained four of them: caffeic acid, p-hydroxybenzoic acid, syringic acid, and vanillic acid. Moreover, shoot extracts also contained salicylic acid (o-hydroxybenzoic acid), while callus extracts contained p-coumaric acid. On the other hand, fruit extracts also contained both salicylic acid and p-coumaric acid. The total amount of the analyzed compounds in extracts from both shoot and callus cultures depended on the L-S medium used, and varied between 103.05 and 150.95 mg 100 g -1 dry weight (DW), and between 50.23 and 81.56 mg 100 g -1 DW, respectively. Both types of culture contained higher levels of phenolic acids than the fruit extracts (32.43 mg 100 g -1 DW). In shoot cultures, p-hydroxybenzoic acid and salicylic acid were the predominant metabolites (reaching 55.14 and 78.25 mg 100 g -1 DW, respectively), while in callus cultures, p-hydroxybenzoic acid (25.60 mg 100 g -1 DW) and syringic acid (41.20 mg 100 g -1 DW) were the main compounds. In fruit extracts, salicylic acid (15.60 mg 100 g -1 DW) and p-hydroxybenzoic acid (5.29 mg 100 g -1 DW) were predominant.

show abstract

“…chlorogenic and rosmarinic acids, are a therapeutically important group of plant metabolites. These compounds possess long-known anti-inflammatory, cholagogic, spasmolytic, hypolipemic and antiaggregatory properties (De Graff et al 2003;Ekiert and Czygan 2007;Nakamura et al 2001;Sroka and Cisowski 2003). More recent studies have also revealed significant antioxidant, anti-free radical, immunostimulating and anticancer activities of some representatives of this group, e.g.…”

Section: Introductionmentioning

confidence: 99%

Production of biologically active phenolic acids in Aronia melanocarpa (Michx.) Elliott in vitro cultures cultivated on different variants of the Murashige and Skoog medium

Szopa

2013

Plant Growth Regul

View full text Add to dashboard Cite

Phenolic acids, both benzoic and cinnamic acid derivatives, are plant metabolites with high therapeutic and cosmetic values. Methanolic extracts from the biomass of shoot and callus cultures of Aronia melanocarpa growing on seven variants of the Murashige and Skoog (MS) medium with different concentrations of plant growth regulators, BA and NAA, ranging from 0.1 to 3.0 mg l -1 , were examined for the production of free phenolic acids and cinnamic acid using the high-performance liquid chromatography (HPLC) method. The extracts from the shoot and callus cultures were confirmed to contain five of the twelve compounds tested for: caffeic, p-coumaric, p-hydroxybenzoic, syringic and vanillic acids. The shoot extracts contained additionally salicylic acid. Both the total amounts and the amounts of individual compounds in either the shoot or callus extracts were dependent on the concentration of cytokinin and auxin in the MS medium variants. The total amounts in the shoot and callus cultures were in the range from 93.52 to 217.00 mg 100 g -1 DW and from 47.11 to 83.83 mg 100 g -1 DW, respectively. The amounts of individual compounds showed wide variation, from 1.31 to 91.86 mg 100 g -1 DW in the shoot extracts, and from 2.58 to 40.16 mg 100 g -1 DW in the callus extracts. Salicylic acid (max. 91.86 mg 100 g -1 DW), p-coumaric acid (max. 62.39 mg 100 g -1 DW) and p-hydroxybenzoic acid (max. 50.66 mg 100 g -1 DW) dominated in the shoot extracts, while syringic acid (max. 40.16 mg 100 g -1 DW) and p-hydroxybenzoic acid (max. 23.59 mg 100 g -1 DW) were the main metabolites in the callus extracts. This is the first report on the quantitative analysis of benzoic and cinnamic acid derivatives in shoot and callus cultures of A. melanocarpa growing on MS-based media with different concentrations of selected plant growth regulators-BA and NAA. The obtained maximum amounts of some metabolites are of interest from a practical perspective.

show abstract

Hydrogen peroxide scavenging, antioxidant and anti-radical activity of some phenolic acids

Cited by 828 publications

References 17 publications

Evaluation of anti–apoptotic activity of different dietary antioxidants in renal cell carcinoma against hydrogen peroxide

Evaluation of anti–apoptotic activity of different dietary antioxidants in renal cell carcinoma against hydrogen peroxide

Accumulation of hydroxybenzoic acids and other biologically active phenolic acids in shoot and callus cultures of Aronia melanocarpa (Michx.) Elliott (black chokeberry)

Production of biologically active phenolic acids in Aronia melanocarpa (Michx.) Elliott in vitro cultures cultivated on different variants of the Murashige and Skoog medium

Contact Info

Product

Resources

About